产品: NUP88 抗体
货号: DF9711
描述: Rabbit polyclonal antibody to NUP88
应用: WB IHC IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 84 kDa,100kDa; 84kD(Calculated).
蛋白号: Q99567
RRID: AB_2842906

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(90%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(90%)
克隆:
Polyclonal
特异性:
NUP88 Antibody detects endogenous levels of total NUP88.
RRID:
AB_2842906
引用格式: Affinity Biosciences Cat# DF9711, RRID:AB_2842906.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

88 kDa nucleoporin; karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein Nup88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin Nup88; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; NUP88; NUP88_HUMAN; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q99567 NUP88_HUMAN:

Ubiquitous.

序列:
MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Pig
90
Chicken
90
Xenopus
70
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q99567 作为底物

Site PTM Type Enzyme
A2 Acetylation
S35 Phosphorylation
T37 Phosphorylation
K41 Ubiquitination
S45 Phosphorylation
S46 Phosphorylation
S49 Phosphorylation
S50 Phosphorylation
T57 Phosphorylation
S96 Phosphorylation
K138 Ubiquitination
K142 Ubiquitination
K150 Ubiquitination
C155 S-Nitrosylation
T166 Phosphorylation
S167 Phosphorylation
S168 Phosphorylation
T169 Phosphorylation
S170 Phosphorylation
T209 Phosphorylation
S221 Phosphorylation
K226 Ubiquitination
T231 Phosphorylation
S233 Phosphorylation
S379 Phosphorylation
S387 Phosphorylation
K394 Ubiquitination
K400 Ubiquitination
K426 Ubiquitination
S430 Phosphorylation
K435 Ubiquitination
S437 Phosphorylation
S442 Phosphorylation
T443 Phosphorylation
K456 Ubiquitination
S496 Phosphorylation
T497 Phosphorylation
S517 Phosphorylation
T525 Phosphorylation
S528 Phosphorylation
K531 Ubiquitination
S540 Phosphorylation
K548 Ubiquitination
K552 Ubiquitination
K579 Ubiquitination
K584 Acetylation
K584 Ubiquitination
K592 Acetylation
K592 Ubiquitination
K598 Ubiquitination
K600 Ubiquitination
S606 Phosphorylation
K625 Ubiquitination
K630 Ubiquitination
K642 Ubiquitination
S646 Phosphorylation
S655 Phosphorylation
K663 Ubiquitination
K680 Ubiquitination
Y688 Phosphorylation
K692 Ubiquitination
K695 Ubiquitination
K712 Ubiquitination
K719 Ubiquitination
K730 Ubiquitination

研究背景

功能:

Component of nuclear pore complex.

细胞定位:

Nucleus>Nuclear pore complex.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

亚基结构:

Interacts with NUP214/CAN. Interacts with NUP62 and NUP98.

研究领域

· Genetic Information Processing > Translation > RNA transport.

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