| 产品: | HSD17B4 抗体 |
| 货号: | DF9735 |
| 描述: | Rabbit polyclonal antibody to HSD17B4 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 80 kDa; 80kD(Calculated). |
| 蛋白号: | P51659 |
| RRID: | AB_2842930 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9735, RRID:AB_2842930.
展开/折叠
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 17 beta HSD 4; 17 beta HSD IV; 17 beta hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; 17-beta-hydroxysteroid dehydrogenase 4; 17beta estradiol dehydrogenase type IV; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase; 3-alpha; 7-alpha; Beta hydroxyacyl dehydrogenase; Beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; D bifunctional protein peroxisomal; D-3-hydroxyacyl CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein; D-bifunctional protein; D-bifunctional protein, peroxisomal; DBP; DBP, peroxisomal; DHB4_HUMAN; EDH17B4; Enoyl-CoA hydratase 2; Hsd17b4; MFE 2; MFE-2; MPF-2; Multifunctional protein 2; Peroxisomal multifunctional enzyme type 2; Peroxisomal multifunctional protein 2; PRLTS1; SDR8C1; Short chain dehydrogenase/reductase family 8C member 1;
抗原和靶标
Present in many tissues with highest concentrations in liver, heart, prostate and testis.
- P51659 DHB4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P51659 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| T15 | Phosphorylation | Uniprot | |
| K46 | Acetylation | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| K57 | Acetylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| K81 | Acetylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| K139 | Acetylation | Uniprot | |
| Y143 | Phosphorylation | Uniprot | |
| T149 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| Y156 | Phosphorylation | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| S185 | Phosphorylation | Uniprot | |
| T265 | Phosphorylation | Uniprot | |
| K270 | Acetylation | Uniprot | |
| K270 | Ubiquitination | Uniprot | |
| K275 | Ubiquitination | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| S300 | Phosphorylation | Uniprot | |
| S304 | Phosphorylation | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| T313 | Phosphorylation | Uniprot | |
| T317 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| T319 | Phosphorylation | Uniprot | |
| S322 | Phosphorylation | Uniprot | |
| Y347 | Phosphorylation | Uniprot | |
| Y414 | Phosphorylation | Uniprot | |
| K415 | Acetylation | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| K424 | Ubiquitination | Uniprot | |
| K565 | Acetylation | Uniprot | |
| K565 | Ubiquitination | Uniprot | |
| K579 | Acetylation | Uniprot | |
| Y602 | Phosphorylation | Uniprot | |
| K621 | Acetylation | Uniprot | |
| K636 | Acetylation | Uniprot | |
| K636 | Ubiquitination | Uniprot | |
| K644 | Acetylation | Uniprot | |
| T655 | Phosphorylation | Uniprot | |
| K669 | Acetylation | Uniprot | |
| K674 | Ubiquitination | Uniprot | |
| K707 | Acetylation | Uniprot | |
| K707 | Ubiquitination | Uniprot | |
| S711 | Phosphorylation | Uniprot | |
| K731 | Acetylation | Uniprot | |
| K731 | Ubiquitination | Uniprot |
研究背景
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Peroxisome.
Present in many tissues with highest concentrations in liver, heart, prostate and testis.
Homodimer.
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
研究领域
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
· Metabolism > Lipid metabolism > Primary bile acid biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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