HSD17B4 Antibody - #DF9735

(1)  
产品: HSD17B4 抗体
货号: DF9735
描述: Rabbit polyclonal antibody to HSD17B4
应用: WB
反应: Human, Mouse
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 80 kDa; 80kD(Calculated).
蛋白号: P51659
RRID: AB_2842930

浏览相似产品>>

   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
HSD17B4 Antibody detects endogenous levels of total HSD17B4.
RRID:
AB_2842930
引用格式: Affinity Biosciences Cat# DF9735, RRID:AB_2842930.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 17 beta HSD 4; 17 beta HSD IV; 17 beta hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; 17-beta-hydroxysteroid dehydrogenase 4; 17beta estradiol dehydrogenase type IV; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase; 3-alpha; 7-alpha; Beta hydroxyacyl dehydrogenase; Beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; D bifunctional protein peroxisomal; D-3-hydroxyacyl CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein; D-bifunctional protein; D-bifunctional protein, peroxisomal; DBP; DBP, peroxisomal; DHB4_HUMAN; EDH17B4; Enoyl-CoA hydratase 2; Hsd17b4; MFE 2; MFE-2; MPF-2; Multifunctional protein 2; Peroxisomal multifunctional enzyme type 2; Peroxisomal multifunctional protein 2; PRLTS1; SDR8C1; Short chain dehydrogenase/reductase family 8C member 1;

抗原和靶标

免疫原:
Uniprot:

P51659(DHB4_HUMAN) >>Visit HPA database.

基因/基因ID:
HSD17B4(3295)
表达:
P51659 DHB4_HUMAN:

Present in many tissues with highest concentrations in liver, heart, prostate and testis.

序列:
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P51659 作为底物

Site PTM Type Enzyme
S3 Phosphorylation
T15 Phosphorylation
K46 Acetylation
K50 Ubiquitination
S52 Phosphorylation
K57 Acetylation
K57 Ubiquitination
K68 Ubiquitination
S75 Phosphorylation
K81 Acetylation
K81 Ubiquitination
S112 Phosphorylation
K139 Acetylation
Y143 Phosphorylation
T149 Phosphorylation
S150 Phosphorylation
S151 Phosphorylation
Y156 Phosphorylation
K184 Ubiquitination
S185 Phosphorylation
T265 Phosphorylation
K270 Acetylation
K270 Ubiquitination
K275 Ubiquitination
S294 Phosphorylation
S300 Phosphorylation
S304 Phosphorylation
S309 Phosphorylation
T313 Phosphorylation
T317 Phosphorylation
S318 Phosphorylation
T319 Phosphorylation
S322 Phosphorylation
Y347 Phosphorylation
Y414 Phosphorylation
K415 Acetylation
K415 Ubiquitination
K424 Ubiquitination
K565 Acetylation
K565 Ubiquitination
K579 Acetylation
Y602 Phosphorylation
K621 Acetylation
K636 Acetylation
K636 Ubiquitination
K644 Acetylation
T655 Phosphorylation
K669 Acetylation
K674 Ubiquitination
K707 Acetylation
K707 Ubiquitination
S711 Phosphorylation
K731 Acetylation
K731 Ubiquitination

研究背景

功能:

Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.

细胞定位:

Peroxisome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Present in many tissues with highest concentrations in liver, heart, prostate and testis.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

研究领域

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

· Metabolism > Lipid metabolism > Primary bile acid biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.