| 产品: | PIGA 抗体 |
| 货号: | DF9742 |
| 描述: | Rabbit polyclonal antibody to PIGA |
| 应用: | WB |
| 反应: | Human, Mouse, Rat, Monkey |
| 分子量: | 54 kDa; 54kD(Calculated). |
| 蛋白号: | P37287 |
| RRID: | AB_2842937 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9742, RRID:AB_2842937.
展开/折叠
Class A GlcNAc inositol phospholipid assembly protein; GlcNAc PI synthesis protein; GlcNAc-PI synthesis protein; GPI3; MCAHS2; Phosphatidylinositol glycan anchor biosynthesis class A; Phosphatidylinositol glycan biosynthesis class A protein; Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; Phosphatidylinositol-glycan biosynthesis class A protein; PIG A; PIG-A; Piga; PIGA_HUMAN;
抗原和靶标
- P37287 PIGA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLPMDKRLDRLISHCGPVTGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGENNEISETR
翻译修饰 - P37287 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R4 | Methylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| T27 | Phosphorylation | Uniprot | |
| T32 | Phosphorylation | Uniprot | |
| Y254 | Phosphorylation | Uniprot | |
| K293 | Ubiquitination | Uniprot | |
| S354 | Phosphorylation | Uniprot | |
| K361 | Ubiquitination | Uniprot | |
| K367 | Ubiquitination | Uniprot | |
| Y385 | Phosphorylation | Uniprot | |
| K396 | Acetylation | Uniprot |
研究背景
Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.
Endoplasmic reticulum membrane>Single-pass membrane protein.
Associates with PIGC, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity. Interacts directly with PIGY.
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
研究领域
· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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