产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9761, RRID:AB_2842956.
展开/折叠
PABP-3; PABP3; PABP3_HUMAN; PABPC3; PABPL3; Poly(A) binding protein 3; Poly(A)-binding protein 3; Polyadenylate binding protein 3; Polyadenylate-binding protein 3; RP11-165I9.5; Testis specific poly(A) binding protein; Testis-specific poly(A)-binding protein; tPABP;
抗原和靶标
- Q9H361 PABP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV
翻译修饰 - Q9H361 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S32 | Phosphorylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| T71 | Phosphorylation | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| K188 | Methylation | Uniprot | |
| Y194 | Phosphorylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K213 | Acetylation | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| S219 | Phosphorylation | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| T224 | Phosphorylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| S230 | Phosphorylation | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| R240 | Methylation | Uniprot | |
| K246 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K259 | Acetylation | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| Y262 | Phosphorylation | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| K284 | Ubiquitination | Uniprot | |
| R309 | Methylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| K333 | Ubiquitination | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| S342 | Phosphorylation | Uniprot | |
| K348 | Ubiquitination | Uniprot | |
| T360 | Phosphorylation | Uniprot | |
| K361 | Ubiquitination | Uniprot | |
| Y364 | Phosphorylation | Uniprot | |
| R426 | Methylation | Uniprot | |
| R430 | Methylation | Uniprot | |
| R437 | Methylation | Uniprot | |
| S458 | Phosphorylation | Uniprot | |
| T459 | Phosphorylation | Uniprot | |
| R461 | Methylation | Uniprot | |
| R469 | Methylation | Uniprot | |
| S480 | Phosphorylation | Uniprot | |
| K601 | Ubiquitination | Uniprot | |
| T630 | Phosphorylation | Uniprot |
研究背景
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.
Cytoplasm.
Testis specific.
Belongs to the polyadenylate-binding protein type-1 family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
· Genetic Information Processing > Translation > mRNA surveillance pathway.
· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.
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