| 产品: | RAB33B 抗体 |
| 货号: | DF9826 |
| 描述: | Rabbit polyclonal antibody to RAB33B |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Dog, Chicken |
| 分子量: | 26 kDa; 26kD(Calculated). |
| 蛋白号: | Q9H082 |
| RRID: | AB_2843020 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9826, RRID:AB_2843020.
展开/折叠
DKFZP434G099; MGC138182; RAB 33B; RAB33B; RAB33B member RAS oncogene family; Ras related protein Rab 33B; Ras related protein Rab33B; Ras-associated protein RAB33B; Ras-related protein Rab-33B; RB33B_HUMAN; SMC2;
抗原和靶标
- Q9H082 RB33B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEEMESSLEASFSSSGAVSGASGFLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVEIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQPPDNGIILKPEPKPAMTCWC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9H082 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T89 | Phosphorylation | Uniprot | |
| S98 | Phosphorylation | Uniprot | |
| K149 | Ubiquitination | Uniprot | |
| K165 | Ubiquitination | Uniprot |
研究背景
Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation.
Golgi apparatus membrane>Lipid-anchor. Golgi apparatus>cis-Golgi network.
Note: Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm.
Interacts with ATG16L. Interaction with ATG16L is important for autophagosome formation (By similarity). Interacts with RIC1 (via C-terminus domain); the interaction is direct with a preference for RAB33B-GTP. Interacts with RGP1.
Belongs to the small GTPase superfamily. Rab family.
研究领域
· Cellular Processes > Transport and catabolism > Autophagy - animal. (View pathway)
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