| 产品: | SHOX 抗体 |
| 货号: | DF9908 |
| 描述: | Rabbit polyclonal antibody to SHOX |
| 应用: | WB |
| 反应: | Human |
| 预测: | Dog |
| 分子量: | 32 kDa; 32kD(Calculated). |
| 蛋白号: | O15266 |
| RRID: | AB_2843102 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9908, RRID:AB_2843102.
展开/折叠
GCFX; Growth control factor, X linked; Homo sapiens shox gene, alternatively spliced products, complete cds; PHOG; Pseudoautosomal homeobox containing osteogenic; Pseudoautosomal homeobox containing osteogenic protein; Pseudoautosomal homeobox-containing osteogenic protein; Short stature homeobox; Short stature homeobox containing protein; Short stature homeobox protein; Short stature homeobox-containing protein; SHOX; SHOX_HUMAN; SHOXY; SS; Turner syndrome;
抗原和靶标
SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
- O15266 SHOX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O15266 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T5 | Phosphorylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K29 | Sumoylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S106 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S120 | Phosphorylation | Uniprot | |
| T125 | Phosphorylation | Uniprot | |
| Y141 | Phosphorylation | Uniprot |
研究背景
Controls fundamental aspects of growth and development.
Nucleus.
SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
Belongs to the paired homeobox family. Bicoid subfamily.
限制条款
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