| 产品: | SFRS9 抗体 |
| 货号: | DF9948 |
| 描述: | Rabbit polyclonal antibody to SFRS9 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 26 kDa; 26kD(Calculated). |
| 蛋白号: | Q13242 |
| RRID: | AB_2843142 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9948, RRID:AB_2843142.
展开/折叠
arginine/serine-rich 9; Pre mRNA splicing factor SRp30C; Pre-mRNA-splicing factor SRp30C; Serine/arginine-rich splicing factor 9; SFRS 9; Splicing factor; Splicing factor arginine/serine rich 9; splicing factor, arginine/serine-rich 9; splicing factor, arginine/serine-rich, 30-KD, C; SR splicing factor 9; SRP30C; SRSF9; SRSF9_HUMAN;
抗原和靶标
Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
- Q13242 SRSF9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q13242 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| R8 | Methylation | Uniprot | |
| Y17 | Phosphorylation | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| K36 | Acetylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| R63 | Methylation | Uniprot | |
| Y70 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| C80 | S-Nitrosylation | Uniprot | |
| R88 | Methylation | Uniprot | |
| R93 | Methylation | Uniprot | |
| R98 | Methylation | Uniprot | |
| R101 | Methylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| R132 | Methylation | Uniprot | |
| Y139 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| Y152 | Phosphorylation | Uniprot | |
| R154 | Methylation | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| Y160 | Phosphorylation | Uniprot | |
| R163 | Methylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| R171 | Methylation | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| Y179 | Phosphorylation | Uniprot | |
| R181 | Methylation | Uniprot | |
| S187 | Phosphorylation | Uniprot | |
| T188 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| Y190 | Phosphorylation | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| R194 | Methylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| Y206 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| R209 | Methylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | P24941 (CDK2) | Uniprot |
| Y221 | Phosphorylation | Uniprot |
研究背景
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
Extensively phosphorylated on serine residues in the RS domain.
Nucleus.
Note: Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
Interacts with KHDRBS3 (By similarity). Interacts with HABP4. Interacts with NOL3/ARC/NOP30. Interacts with NSEP1/YB-1/YB1. Interacts with SAFB/SAFB1. Interacts with SRSF6/SFRS6. Interacts with TRA2B/SFRS10. Interacts with C1QBP. May also interact with DUSP11/PIR1.
Belongs to the splicing factor SR family.
研究领域
· Genetic Information Processing > Transcription > Spliceosome.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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