产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9956, RRID:AB_2843150.
展开/折叠
STX 6; STX6; STX-6; STX6_HUMAN; Syntaxin-6; Syntaxin6;
抗原和靶标
- O43752 STX6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLVL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O43752 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K77 | Ubiquitination | Uniprot | |
| T83 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| K89 | Ubiquitination | Uniprot | |
| S107 | Phosphorylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| T134 | Phosphorylation | Uniprot | |
| T137 | Phosphorylation | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| Y140 | Phosphorylation | Uniprot | |
| S152 | Phosphorylation | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| T229 | Phosphorylation | Uniprot | |
| S230 | Phosphorylation | Uniprot |
研究背景
Involved in intracellular vesicle trafficking.
Golgi apparatus membrane>Single-pass type IV membrane protein.
Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Binds EEA1 (By similarity). Interacts with VPS45A (By similarity). Interacts with MARCHF2 and MARCHF3 (By similarity). Interacts with GOPC. Interacts with UHRF1BP1L (via C-terminal coiled-coil domain). Interacts with BAIAP3; this interaction is increased in the presence of calcium.
Belongs to the syntaxin family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.
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