| 产品: | MPHOSPH10 抗体 |
| 货号: | DF9977 |
| 描述: | Rabbit polyclonal antibody to MPHOSPH10 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 20,70 kDa; 79kD(Calculated). |
| 蛋白号: | O00566 |
| RRID: | AB_2843169 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9977, RRID:AB_2843169.
展开/折叠
M phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); M phase phosphoprotein 10; MPHOSPH 10; Mphosph10; MPP 10; MPP 10P; MPP10; MPP10_HUMAN; MPP10P; U3 small nucleolar ribonucleoprotein protein mpp10;
抗原和靶标
- O00566 MPP10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDIKTAAEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQAGKYSKTVASEKLKQLTKTGKASFIKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKRQDISVHKLKL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O00566 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T10 | Phosphorylation | Uniprot | |
| T22 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| K38 | Ubiquitination | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S158 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| K185 | Sumoylation | Uniprot | |
| K189 | Acetylation | Uniprot | |
| K193 | Acetylation | Uniprot | |
| K197 | Acetylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| S275 | Phosphorylation | Uniprot | |
| T280 | Phosphorylation | Uniprot | |
| S289 | Phosphorylation | Uniprot | |
| S305 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| T309 | Phosphorylation | Uniprot | |
| T332 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| T341 | Phosphorylation | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| K376 | Ubiquitination | Uniprot | |
| K382 | Sumoylation | Uniprot | |
| S399 | Phosphorylation | Uniprot | |
| T418 | Phosphorylation | Uniprot | |
| Y452 | Phosphorylation | Uniprot | |
| Y454 | Phosphorylation | Uniprot | |
| T459 | Phosphorylation | Uniprot | |
| K466 | Ubiquitination | Uniprot | |
| Y477 | Phosphorylation | Uniprot | |
| K479 | Ubiquitination | Uniprot | |
| K484 | Ubiquitination | Uniprot | |
| K498 | Ubiquitination | Uniprot | |
| S502 | Phosphorylation | Uniprot | |
| K518 | Ubiquitination | Uniprot | |
| K559 | Acetylation | Uniprot | |
| K564 | Acetylation | Uniprot | |
| K574 | Acetylation | Uniprot | |
| K609 | Acetylation | Uniprot | |
| S629 | Phosphorylation | Uniprot | |
| K632 | Sumoylation | Uniprot | |
| K641 | Methylation | Uniprot |
研究背景
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
Phosphorylated in M (mitotic) phase.
Nucleus>Nucleolus. Chromosome.
Note: Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966).
Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with IMP3 and IMP4.
Belongs to the MPP10 family.
研究领域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
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