SART1 Antibody - #DF9978

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产品: SART1 抗体
货号: DF9978
描述: Rabbit polyclonal antibody to SART1
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Xenopus
分子量: 90 kDa; 90kD(Calculated).
蛋白号: O43290
RRID: AB_2843170

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Xenopus(83%)
克隆:
Polyclonal
特异性:
SART1 Antibody detects endogenous levels of total SART1.
RRID:
AB_2843170
引用格式: Affinity Biosciences Cat# DF9978, RRID:AB_2843170.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Ara 1; ARA1; HOMS 1; HOMS1; hSART 1; hSART1; hSnu 66; hSnu66; IgE autoantigen; MGC2038; SART 1; SART1 259; SART1(259) protein; SART1(800) protein; SART1259; Snu 66; Snu66; Squamous cell carcinoma antigen recognised by T cells; Squamous cell carcinoma antigen recognized by T cells 1; U4/U6.U5 tri snRNP associated 110 kDa protein; U4/U6.U5 tri snRNP associated protein 1;

抗原和靶标

免疫原:
Uniprot:

O43290(SNUT1_HUMAN) >>Visit HPA database.

基因/基因ID:
SART1(9092)
表达:
O43290 SNUT1_HUMAN:

Ubiquitously expressed.

序列:
MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
100
Xenopus
83
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O43290 作为底物

Site PTM Type Enzyme
T22 Phosphorylation
S42 Phosphorylation
S45 Phosphorylation
S48 Phosphorylation
S84 Phosphorylation
K94 Sumoylation
Y102 Phosphorylation
S108 Phosphorylation
K109 Ubiquitination
S111 Phosphorylation
S112 Phosphorylation
S119 Phosphorylation
T123 Phosphorylation
K125 Ubiquitination
K129 Ubiquitination
K133 Acetylation
K133 Ubiquitination
K141 Sumoylation
K147 Sumoylation
K147 Ubiquitination
K183 Ubiquitination
K188 Sumoylation
K188 Ubiquitination
T189 Phosphorylation
T200 Phosphorylation
Y249 Phosphorylation
S250 Phosphorylation
T258 Phosphorylation
S265 Phosphorylation
T271 Phosphorylation
T275 Phosphorylation
K302 Ubiquitination
Y316 Phosphorylation
S321 Phosphorylation
K329 Ubiquitination
S332 Phosphorylation
S335 Phosphorylation
K336 Ubiquitination
S348 Phosphorylation
R385 Methylation
S388 Phosphorylation
Y390 Phosphorylation
T392 Phosphorylation
K400 Ubiquitination
T430 Phosphorylation
S437 Phosphorylation
S448 Phosphorylation
S463 Phosphorylation
T466 Phosphorylation
S474 Phosphorylation
S486 Phosphorylation
S521 Phosphorylation
K524 Ubiquitination
K530 Ubiquitination
S591 Phosphorylation
S596 Phosphorylation
S598 Phosphorylation
S621 Phosphorylation
S623 Phosphorylation
K648 Ubiquitination
K657 Ubiquitination
K666 Ubiquitination
S667 Phosphorylation
Y673 Phosphorylation
K678 Ubiquitination
K684 Ubiquitination
Y685 Phosphorylation
S686 Phosphorylation
R692 Methylation
T695 Phosphorylation
K699 Ubiquitination
K709 Sumoylation
Y712 Phosphorylation
K719 Ubiquitination
T721 Phosphorylation
K723 Ubiquitination
S730 Phosphorylation
K742 Sumoylation
K749 Ubiquitination
K757 Methylation
K758 Methylation
K758 Sumoylation
K758 Ubiquitination
S760 Phosphorylation
S761 Phosphorylation
S762 Phosphorylation
T764 Phosphorylation
T768 Phosphorylation
K775 Ubiquitination
T781 Phosphorylation
Y783 Phosphorylation
S789 Phosphorylation

研究背景

功能:

Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA.

翻译修饰:

Sumoylated with SUMO2.

细胞定位:

Nucleus.
Note: Found in the nucleus of mitogen-activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitously expressed.

亚基结构:

Identified in the spliceosome C complex. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39.

蛋白家族:

Belongs to the SNU66/SART1 family.

研究领域

· Genetic Information Processing > Transcription > Spliceosome.

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