| 产品: | GBP4 抗体 |
| 货号: | AF9071 |
| 描述: | Rabbit polyclonal antibody to GBP4 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 分子量: | 73kDa; 73kD(Calculated). |
| 蛋白号: | Q96PP9 |
| RRID: | AB_2843262 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF9071, RRID:AB_2843262.
展开/折叠
GBP 4; GBP-4; GBP4; GBP4_HUMAN; GTP binding protein 4; GTP-binding protein 4; Guanine nucleotide binding protein 4; Guanine nucleotide-binding protein 4; Guanylate binding protein 4; Guanylate-binding protein 4; Mpa2;
抗原和靶标
- Q96PP9 GBP4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKILDMASNIMIVTLPGASKLLGVGTKYLGSRI
翻译修饰 - Q96PP9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T303 | Phosphorylation | Uniprot | |
| T401 | Phosphorylation | Uniprot | |
| K404 | Acetylation | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| T433 | Phosphorylation | Uniprot | |
| S435 | Phosphorylation | Uniprot | |
| S537 | Phosphorylation | Uniprot | |
| K567 | Acetylation | Uniprot | |
| S615 | Phosphorylation | Uniprot | |
| K634 | Ubiquitination | Uniprot |
研究背景
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).
Cytoplasm. Nucleus. Cytoplasm>Perinuclear region. Golgi apparatus membrane.
Note: Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
Heterodimer with other family members, including GBP1, GBP2 and GBP5. Dimerization regulates subcellular location.
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.
研究领域
· Organismal Systems > Immune system > NOD-like receptor signaling pathway. (View pathway)
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