| 产品: | WBSCR11 抗体 |
| 货号: | AF9231 |
| 描述: | Rabbit polyclonal antibody to WBSCR11 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 106kDa; 106kD(Calculated). |
| 蛋白号: | Q9UHL9 |
| RRID: | AB_2843421 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF9231, RRID:AB_2843421.
展开/折叠
CREAM1; General transcription factor II I repeat domain containing protein 1; General transcription factor II-I repeat domain-containing protein 1; General transcription factor III; GT2D1_HUMAN; GTF2I repeat domain containing protein 1; GTF2I repeat domain-containing protein 1; GTF2IRD1; GTF3; Muscle TFII I repeat domain-containing protein 1; Muscle TFII-I repeat domain-containing protein 1; MUSTRD1; MusTRD1/BEN; RBAP2; Slow muscle fiber enhancer binding protein; Slow-muscle-fiber enhancer-binding protein; USE B1 binding protein; USE B1-binding protein; WBSCR11; WBSCR12; Williams Beuren syndrome chromosome region 11 protein; Williams-Beuren syndrome chromosomal region 11 protein; Williams-Beuren syndrome chromosomal region 12 protein;
抗原和靶标
Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.
- Q9UHL9 GT2D1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9UHL9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K94 | Ubiquitination | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| K130 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| K212 | Sumoylation | Uniprot | |
| K225 | Sumoylation | Uniprot | |
| K271 | Sumoylation | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K308 | Sumoylation | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| S329 | Phosphorylation | Uniprot | |
| K337 | Sumoylation | Uniprot | |
| K337 | Ubiquitination | Uniprot | |
| K379 | Sumoylation | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| K395 | Ubiquitination | Uniprot | |
| T403 | Phosphorylation | Uniprot | |
| Y404 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| K436 | Sumoylation | Uniprot | |
| K436 | Ubiquitination | Uniprot | |
| K443 | Sumoylation | Uniprot | |
| K443 | Ubiquitination | Uniprot | |
| S448 | Phosphorylation | Uniprot | |
| T461 | Phosphorylation | Uniprot | |
| S471 | Phosphorylation | Uniprot | |
| S475 | Phosphorylation | Uniprot | |
| S477 | Phosphorylation | Uniprot | |
| K495 | Sumoylation | Uniprot | |
| K567 | Sumoylation | Uniprot | |
| Y577 | Phosphorylation | Uniprot | |
| K579 | Sumoylation | Uniprot | |
| K579 | Ubiquitination | Uniprot | |
| S584 | Phosphorylation | Uniprot | |
| K638 | Sumoylation | Uniprot | |
| S654 | Phosphorylation | Uniprot | |
| K684 | Sumoylation | Uniprot | |
| K684 | Ubiquitination | Uniprot | |
| T704 | Phosphorylation | Uniprot | |
| K715 | Ubiquitination | Uniprot | |
| K716 | Ubiquitination | Uniprot | |
| Y717 | Phosphorylation | Uniprot | |
| K724 | Sumoylation | Uniprot | |
| K724 | Ubiquitination | Uniprot | |
| K754 | Ubiquitination | Uniprot | |
| K787 | Sumoylation | Uniprot | |
| K799 | Ubiquitination | Uniprot | |
| K807 | Ubiquitination | Uniprot | |
| Y814 | Phosphorylation | Uniprot | |
| Y828 | Phosphorylation | Uniprot | |
| K829 | Sumoylation | Uniprot | |
| K829 | Ubiquitination | Uniprot | |
| S834 | Phosphorylation | Uniprot | |
| S906 | Phosphorylation | Uniprot | |
| S914 | Phosphorylation | Uniprot | |
| S915 | Phosphorylation | Uniprot | |
| S916 | Phosphorylation | Uniprot | |
| S917 | Phosphorylation | Uniprot |
研究背景
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity).
Nucleus.
Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.
Interacts with the retinoblastoma protein (RB1) via its C-terminus.
The N-terminal half may have an activating activity.
Belongs to the TFII-I family.
研究领域
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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