| 产品: | Gz alpha 抗体 |
| 货号: | AF0091 |
| 描述: | Rabbit polyclonal antibody to Gz alpha |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 41kDa; 41kD(Calculated). |
| 蛋白号: | P19086 |
| RRID: | AB_2833274 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0091, RRID:AB_2833274.
展开/折叠
G(x) alpha chain; GNAZ; GNAZ_HUMAN; Guanine nucleotide binding protein (G protein) alpha z polypeptide; Guanine nucleotide binding protein G(z) alpha subunit G(x) alpha chain; Guanine nucleotide binding protein G(z) subunit alpha; Guanine nucleotide-binding protein G(z) subunit alpha; Gz alpha; Gz-alpha; Human Gx alpha gene; Transducin alpha;
抗原和靶标
- P19086 GNAZ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P19086 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S16 | Phosphorylation | Q05655 (PRKCD) , Q13153 (PAK1) , P17252 (PRKCA) | Uniprot |
| S27 | Phosphorylation | P17252 (PRKCA) , Q05655 (PRKCD) | Uniprot |
| T41 | Phosphorylation | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| T341 | Phosphorylation | Uniprot |
研究背景
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Membrane>Lipid-anchor.
G-proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with ADGRB2.
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
研究领域
· Organismal Systems > Nervous system > Long-term depression.
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