KIF20A Antibody - #AF7664

>>买2送1 进行中>>
>>满百送 进行中>>
>>赠送JD卡 进行中>>
>>3倍积分 进行中>>
(2)  
产品: KIF20A 抗体
货号: AF7664
描述: Rabbit polyclonal antibody to KIF20A
应用: WB IF/ICC
反应: Human
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 100kDa; 100kD(Calculated).
蛋白号: O95235
RRID: AB_2844028

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(89%), Dog(100%), Xenopus(86%)
克隆:
Polyclonal
特异性:
KIF20A Antibody detects endogenous levels of total KIF20A.
RRID:
AB_2844028
引用格式: Affinity Biosciences Cat# AF7664, RRID:AB_2844028.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AA415432; FLJ21151; GG10 2; GG10_2; KI20A_HUMAN; KIF20A; kinesin family member 20A; Kinesin like protein KIF20A; Kinesin-like protein 174; Kinesin-like protein KIF20A; mitotic kinesin like protein 2; Mitotic kinesin-like protein 2; MKlp2; OTTHUMP00000159481; RAB6 interacting, kinesin like (rabkinesin6); Rab6-interacting kinesin-like protein; RAB6-INTERACTING PROTEIN, KINESIN-LIKE; RAB6KIFL; Rabkinesin 6; Rabkinesin-6;

抗原和靶标

免疫原:
Uniprot:

O95235(KI20A_HUMAN) >>Visit HPA database.

基因/基因ID:
KIF20A(10112)
序列:
MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFSIWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPNQQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
89
Xenopus
86
Zebrafish
57
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O95235 作为底物

Site PTM Type Enzyme
S2 Acetylation
S2 Phosphorylation
S7 Phosphorylation
S14 Phosphorylation
S21 Phosphorylation
S33 Phosphorylation
K37 Ubiquitination
S41 Phosphorylation
S44 Phosphorylation
S47 Phosphorylation
S49 Phosphorylation
S58 Phosphorylation
S61 Phosphorylation
K102 Ubiquitination
K108 Ubiquitination
S109 Phosphorylation
K150 Ubiquitination
K175 Ubiquitination
T198 Phosphorylation
K215 Ubiquitination
K224 Ubiquitination
S226 Phosphorylation
S240 Phosphorylation
K242 Ubiquitination
S244 Phosphorylation
Y246 Phosphorylation
S249 Phosphorylation
T255 Phosphorylation
S256 Phosphorylation
S259 Phosphorylation
S274 Phosphorylation
K342 Ubiquitination
K357 Ubiquitination
K364 Ubiquitination
S405 Phosphorylation
K425 Ubiquitination
K453 Ubiquitination
S522 Phosphorylation
S528 Phosphorylation
S532 Phosphorylation
K537 Ubiquitination
K540 Ubiquitination
T543 Phosphorylation
S556 Phosphorylation
Y558 Phosphorylation
T572 Phosphorylation
K576 Ubiquitination
K581 Ubiquitination
K625 Ubiquitination
K630 Ubiquitination
S632 Phosphorylation
S635 Phosphorylation
Y637 Phosphorylation
K647 Ubiquitination
S662 Phosphorylation
S668 Phosphorylation
S670 Phosphorylation
S677 Phosphorylation
S683 Phosphorylation
S685 Phosphorylation
T686 Phosphorylation
K693 Ubiquitination
S705 Phosphorylation
T706 Phosphorylation
K712 Ubiquitination
K739 Ubiquitination
K750 Ubiquitination
S754 Phosphorylation
S757 Phosphorylation
K819 Ubiquitination
S825 Phosphorylation
K827 Ubiquitination
T832 Phosphorylation
T857 Phosphorylation
T859 Phosphorylation
S862 Phosphorylation
S863 Phosphorylation
T864 Phosphorylation
S867 Phosphorylation
Y869 Phosphorylation
S875 Phosphorylation
S878 Phosphorylation Q96GD4 (AURKB)
S883 Phosphorylation

研究背景

功能:

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.

翻译修饰:

Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle.

细胞定位:

Golgi apparatus. Cytoplasm>Cytoskeleton>Spindle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.