| 产品: | REPS1 抗体 |
| 货号: | AF7931 |
| 描述: | Rabbit polyclonal antibody to REPS1 |
| 应用: | WB |
| 反应: | Human, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Chicken |
| 分子量: | 80~110kD; 87kD(Calculated). |
| 蛋白号: | Q96D71 |
| RRID: | AB_2844294 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF7931, RRID:AB_2844294.
展开/折叠
RALBP1; RalBP1 associated Eps domain containing protein 1; RalBP1 interacting protein 1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1; REPS1; REPS1_HUMAN;
抗原和靶标
- Q96D71 REPS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q96D71 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K27 | Ubiquitination | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S110 | Phosphorylation | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| Y116 | Phosphorylation | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| Y126 | Phosphorylation | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| S145 | Phosphorylation | Uniprot | |
| T148 | Phosphorylation | Uniprot | |
| T153 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S166 | Phosphorylation | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| T173 | Phosphorylation | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| T177 | Phosphorylation | Uniprot | |
| S186 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| T264 | Phosphorylation | Uniprot | |
| S272 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| S274 | Phosphorylation | Uniprot | |
| Y275 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| S377 | Phosphorylation | Uniprot | |
| Y389 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| S392 | Phosphorylation | Uniprot | |
| S399 | Phosphorylation | Uniprot | |
| S401 | Phosphorylation | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| T459 | Phosphorylation | Uniprot | |
| S461 | Phosphorylation | Uniprot | |
| K462 | Ubiquitination | Uniprot | |
| K471 | Methylation | Uniprot | |
| T473 | Phosphorylation | Uniprot | |
| S475 | Phosphorylation | Uniprot | |
| T478 | Phosphorylation | Uniprot | |
| T481 | Phosphorylation | Uniprot | |
| S482 | Phosphorylation | Uniprot | |
| S489 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| S515 | Phosphorylation | Uniprot | |
| S518 | Phosphorylation | Uniprot | |
| S535 | Phosphorylation | Uniprot | |
| S537 | Phosphorylation | Uniprot | |
| T539 | Phosphorylation | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| T544 | Phosphorylation | Uniprot | |
| S556 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S560 | Phosphorylation | Uniprot | |
| S561 | Phosphorylation | Uniprot | |
| S562 | Phosphorylation | Uniprot | |
| S667 | Phosphorylation | Uniprot | |
| T694 | Phosphorylation | Uniprot | |
| K708 | Ubiquitination | Uniprot | |
| S709 | Phosphorylation | Uniprot | |
| T721 | Phosphorylation | Uniprot | |
| S736 | Phosphorylation | Uniprot | |
| S740 | Phosphorylation | Uniprot | |
| S751 | Phosphorylation | Uniprot | |
| T758 | Phosphorylation | Uniprot | |
| S767 | Phosphorylation | Uniprot | |
| S794 | Phosphorylation | Uniprot |
研究背景
May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.
EGF stimulates phosphorylation on Tyr-residues.
Membrane>Clathrin-coated pit.
Note: Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
Widely expressed with highest levels in heart and testis.
Homodimer (Potential). Interacts with RAB11FIP2. Interacts with RALBP1, CRK and GRB2. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2 which may link it to an EGF-responsive tyrosine kinase (By similarity). Interacts with AMPH, ITSN1 (via SH3 domains) and SGIP1; may be involved in clathrin-mediated endocytosis.
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