| 产品: | NAKED1 抗体 |
| 货号: | AF4646 |
| 描述: | Rabbit polyclonal antibody to NAKED1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 52kDa; 52kD(Calculated). |
| 蛋白号: | Q969G9 |
| RRID: | AB_2844588 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF4646, RRID:AB_2844588.
展开/折叠
Dvl-binding protein; Naked cuticle 1; naked cuticle 1 homolog; Naked cuticle homolog 1 (Drosophila); Naked-1; NKD; Nkd1; Protein naked cuticle homolog 1;
抗原和靶标
Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen.
- Q969G9 NKD1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGGVSGPRQLRLAGTIGRSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKKMERVSEPCPGSKKQLKFEELQCDVSMEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKMLRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLEQSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSNPTRSRSHEPEAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPLASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q969G9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S17 | Phosphorylation | Uniprot | |
| S48 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| T94 | Phosphorylation | Uniprot | |
| S99 | Phosphorylation | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S222 | Phosphorylation | Uniprot | |
| Y245 | Phosphorylation | Uniprot | |
| Y259 | Phosphorylation | Uniprot | |
| Y268 | Phosphorylation | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| T323 | Phosphorylation | Uniprot | |
| S348 | Phosphorylation | Uniprot | |
| R363 | Methylation | Uniprot | |
| Y441 | Phosphorylation | Uniprot |
研究背景
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
Cell membrane. Cytoplasm.
Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen.
Interacts with DVL1, DVL2, DVL3 and PPP2R3A.
Belongs to the NKD family.
研究领域
· Environmental Information Processing > Signal transduction > Wnt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Hippo signaling pathway. (View pathway)
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