PPIG Antibody - #AF4766

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产品: PPIG 抗体
货号: AF4766
描述: Rabbit polyclonal antibody to PPIG
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 110kDa; 89kD(Calculated).
蛋白号: Q13427
RRID: AB_2844606

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(92%)
克隆:
Polyclonal
特异性:
PPIG Antibody detects endogenous levels of total PPIG.
RRID:
AB_2844606
引用格式: Affinity Biosciences Cat# AF4766, RRID:AB_2844606.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CARS cyclophilin; CARS Cyp; CARS-cyclophilin; CARS-Cyp; CASP 10; CASP10; Clk associating RS cyclophilin; Clk-associating RS-cyclophilin; Cyclophilin G; CyclophilinG; CYP; MGC133241; Peptidyl prolyl cis trans isomerase G; Peptidyl prolyl isomerase G (cyclophilin G); Peptidyl prolyl isomerase G; Peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; Peptidylprolyl isomerase G (cyclophilin G); Peptidylprolyl isomerase G; PPIase G; Ppig; PPIG_HUMAN; Rotamase G; RotamaseG; SCAF10; SR cyclophilin; SR cyp; SR related CTD associated factor 10; SR-cyclophilin; SR-cyp; SRcyp;

抗原和靶标

免疫原:
Uniprot:

Q13427(PPIG_HUMAN) >>Visit HPA database.

基因/基因ID:
PPIG(9360)
表达:
Q13427 PPIG_HUMAN:

Ubiquitous.

序列:
MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
92
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q13427 作为底物

Site PTM Type Enzyme
K158 Ubiquitination
S173 Phosphorylation
K182 Ubiquitination
S193 Phosphorylation
S195 Phosphorylation
S196 Phosphorylation
S197 Phosphorylation
S198 Phosphorylation
S199 Phosphorylation
S200 Phosphorylation
S201 Phosphorylation
S202 Phosphorylation
S204 Phosphorylation
S206 Phosphorylation
S207 Phosphorylation
S208 Phosphorylation
S212 Phosphorylation
S214 Phosphorylation
S217 Phosphorylation
S219 Phosphorylation
T223 Phosphorylation
S254 Phosphorylation
S256 Phosphorylation
S257 Phosphorylation
S259 Phosphorylation
S290 Phosphorylation
S315 Phosphorylation
Y320 Phosphorylation
T343 Phosphorylation
S345 Phosphorylation
S347 Phosphorylation
S349 Phosphorylation
S356 Phosphorylation
T358 Phosphorylation
S375 Phosphorylation
S376 Phosphorylation
S386 Phosphorylation
S397 Phosphorylation
T407 Phosphorylation
S413 Phosphorylation
S415 Phosphorylation
S431 Phosphorylation
S433 Phosphorylation
S442 Phosphorylation
K447 Acetylation
K449 Acetylation
K459 Ubiquitination
K463 Ubiquitination
S487 Phosphorylation
S489 Phosphorylation
S527 Phosphorylation
S544 Phosphorylation
S546 Phosphorylation
T552 Phosphorylation
Y558 Phosphorylation
S560 Phosphorylation
S566 Phosphorylation
S568 Phosphorylation
S572 Phosphorylation
S587 Phosphorylation
T611 Phosphorylation
S628 Phosphorylation
S630 Phosphorylation
S631 Phosphorylation
S638 Phosphorylation
S666 Phosphorylation
S673 Phosphorylation
S674 Phosphorylation
S677 Phosphorylation
S687 Phosphorylation
S690 Phosphorylation
S696 Phosphorylation
S716 Phosphorylation
S717 Phosphorylation
K720 Acetylation
K724 Acetylation
S744 Phosphorylation
S745 Phosphorylation
T748 Phosphorylation
S753 Phosphorylation

研究背景

功能:

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.

细胞定位:

Nucleus matrix. Nucleus speckle.
Note: Colocalizes with RNA splicing factors at nuclear speckles.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

亚基结构:

Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.

蛋白家族:

The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.

限制条款

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