Catenin-1 Antibody - #AF4684

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产品: Catenin-1 抗体
货号: AF4684
描述: Rabbit polyclonal antibody to Catenin-1
应用: WB
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Xenopus
蛋白号: O60716
RRID: AB_2844689

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Catenin-1 Antibody detects endogenous levels of total Catenin-1.
RRID:
AB_2844689
引用格式: Affinity Biosciences Cat# AF4684, RRID:AB_2844689.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin (cadherin associated protein) delta 1; Catenin delta 1; Catenin delta; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN;

抗原和靶标

免疫原:

A synthesized peptide derived from human Catenin-1, corresponding to a region within the internal amino acids.

基因/基因ID:
CTNND1(1500)

研究领域

· Cellular Processes > Cellular community - eukaryotes > Adherens junction.   (View pathway)

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Leukocyte transendothelial migration.   (View pathway)

文献引用

1). LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway. International Immunopharmacology, 2020 (PubMed: 33096360) [IF=4.8]

Application: WB    Species: rat    Sample: brain

Fig. 3. |LXA4 intervention may prevent BBB disruption following HI brain damage in neonatal rats. (C)Protein expression level of P120 and β-catenin 24 h after HI brain injury.

Application: WB    Species: Rat    Sample: brain tissue

Fig. 3. LXA4 intervention may prevent BBB disruption following HI brain damage in neonatal rats. (A) Representative results of Evans Blue-stained brain 24 h after HI brain injury. (B) Calculation of Evans blue content in the brain. ****P < 0.0001 versus the Sham + NS group, ##P < 0.01 versus the HI + NS group. n = 5. (C) Protein expression level of P120 and β-catenin 24 h after HI brain injury. (D, E) Analyses of P120 and β-catenin (of β-actin). ***P < 0.001 and ****P < 0.0001versus the Sham + NS group, #P < 0.05 and #P < 0.05 versus the HI + NS group. n = 3. (F) Protein expression level of Occludin and Claudin-5, 24 h after HI brain injury. (G, H) Analyses of Occludin and Claudin-5 (of β-actin). *****P < 0.0001 versus the Sham + NS group, ##P < 0.01 and ##P < 0.001 versus the HI + NS group. n = 3.
2). Indole-3-propionic Acid Attenuates HI-Related Blood–Brain Barrier Injury in Neonatal Rats by Modulating the PXR Signaling Pathway. ACS Chemical Neuroscience, 2022 (PubMed: 36129348) [IF=4.1]

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