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| 产品: | PLOD2 抗体 |
| 货号: | DF12018 |
| 描述: | Rabbit polyclonal antibody to PLOD2 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 85 kDa; 85kD(Calculated). |
| 蛋白号: | O00469 |
| RRID: | AB_2844823 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12018, RRID:AB_2844823.
展开/折叠
2-oxoglutarate 5-dioxygenase 2; LH2; Lysine hydroxylase 2; Lysyl hydroxylase 2; OTTHUMP00000215204; OTTHUMP00000215205; OTTHUMP00000215206; PLOD 2; Plod2; PLOD2_HUMAN; Procollagen lysine 2 oxoglutarate 5 dioxygenase 2; Procollagen lysine, 2 oxoglutarate 5 dioxygenase (lysine hydroxylase) 2; Procollagen-lysine; Telopeptide lysyl hydroxylase; TLH;
抗原和靶标
Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta.
- O00469 PLOD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O00469 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R76 | Methylation | Uniprot | |
| K89 | Ubiquitination | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| K153 | Ubiquitination | Uniprot | |
| Y163 | Phosphorylation | Uniprot | |
| Y172 | Phosphorylation | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| N209 | N-Glycosylation | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| T320 | Phosphorylation | Uniprot | |
| Y323 | Phosphorylation | Uniprot | |
| K329 | Ubiquitination | Uniprot | |
| K335 | Ubiquitination | Uniprot | |
| K341 | Ubiquitination | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| K355 | Ubiquitination | Uniprot | |
| K358 | Ubiquitination | Uniprot | |
| Y387 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| K412 | Ubiquitination | Uniprot | |
| Y444 | Phosphorylation | Uniprot | |
| K486 | Ubiquitination | Uniprot | |
| N522 | N-Glycosylation | Uniprot | |
| K543 | Ubiquitination | Uniprot | |
| K588 | Ubiquitination | Uniprot | |
| S590 | Phosphorylation | Uniprot | |
| K593 | Ubiquitination | Uniprot | |
| S600 | Phosphorylation | Uniprot | |
| T608 | Phosphorylation | Uniprot | |
| T634 | Phosphorylation | Uniprot | |
| Y655 | Phosphorylation | Uniprot | |
| S656 | Phosphorylation | Uniprot | |
| K704 | Acetylation | Uniprot |
研究背景
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Rough endoplasmic reticulum membrane>Peripheral membrane protein>Lumenal side.
Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta.
Homodimer.
研究领域
· Metabolism > Amino acid metabolism > Lysine degradation.
文献引用
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