| 产品: | GNMT 抗体 |
| 货号: | DF12117 |
| 描述: | Rabbit polyclonal antibody to GNMT |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 33 kDa; 33kD(Calculated). |
| 蛋白号: | Q14749 |
| RRID: | AB_2844922 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12117, RRID:AB_2844922.
展开/折叠
EC 2.1.1.20; Glycine N methyltransferase; Glycine N-methyltransferase; Gnmt; GNMT_HUMAN; OTTHUMP00000016412;
抗原和靶标
- Q14749 GNMT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q14749 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| Y22 | Phosphorylation | Uniprot | |
| Y34 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K97 | Acetylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y197 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T220 | Phosphorylation | Uniprot | |
| T224 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot |
研究背景
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Cytoplasm.
Abundant in liver.
Homotetramer.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
研究领域
· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.
限制条款
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