| 产品: | PPAT 抗体 |
| 货号: | DF12131 |
| 描述: | Rabbit polyclonal antibody to PPAT |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 50-56kd; 57kD(Calculated). |
| 蛋白号: | Q06203 |
| RRID: | AB_2844936 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12131, RRID:AB_2844936.
展开/折叠
Amidophosphoribosyltransferase [Precursor]; Amidophosphoribosyltransferase; ATase; Glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; Glutamine PRPP amidotransferase; GPAT; Phosphoribosyl pyrophosphate amidotransferase; Ppat; PRAT; PUR1_HUMAN;
抗原和靶标
- Q06203 PUR1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKEKKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q06203 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| K62 | Acetylation | Uniprot | |
| K62 | Methylation | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| K65 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| K81 | Acetylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| K99 | Acetylation | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| R130 | Methylation | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| K178 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| C339 | S-Nitrosylation | Uniprot | |
| C348 | S-Nitrosylation | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| T356 | Phosphorylation | Uniprot | |
| K371 | Acetylation | Uniprot | |
| K372 | Acetylation | Uniprot | |
| K372 | Ubiquitination | Uniprot | |
| K381 | Ubiquitination | Uniprot | |
| K383 | Methylation | Uniprot | |
| S399 | Phosphorylation | Uniprot | |
| K403 | Ubiquitination | Uniprot | |
| K406 | Ubiquitination | Uniprot | |
| S408 | Phosphorylation | Uniprot | |
| K411 | Ubiquitination | Uniprot | |
| K482 | Acetylation | Uniprot | |
| K499 | Acetylation | Uniprot | |
| K510 | Ubiquitination | Uniprot |
研究背景
Ubiquitously expressed.
Homotetramer.
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
研究领域
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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