| 产品: | ELAC2 抗体 |
| 货号: | DF12153 |
| 描述: | Rabbit polyclonal antibody to ELAC2 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 92 kDa; 92kD(Calculated). |
| 蛋白号: | Q9BQ52 |
| RRID: | AB_2844958 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12153, RRID:AB_2844958.
展开/折叠
COXPD17; elaC homolog 2 (E. coli); ElaC homolog protein 2; elaC ribonuclease Z 2; elaC, E. coli, homolog of, 2; ELAC2; ELC2; FLJ10530; FLJ36693; FLJ42848; Heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; Ribonuclease Z 2; Ribonuclease Z, long form; Ribonuclease Z2; RNase Z 2; RNase Z2; RNase ZL; RNZ2_HUMAN; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; tRNase Z2; Zinc phosphodiesterase ELAC protein 2;
抗原和靶标
Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
- Q9BQ52 RNZ2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSSDSESNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFRCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEEPQAKKVRAQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9BQ52 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R28 | Methylation | Uniprot | |
| K99 | Methylation | Uniprot | |
| K101 | Methylation | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K152 | Acetylation | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| Y181 | Phosphorylation | Uniprot | |
| K193 | Ubiquitination | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S215 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| K260 | Ubiquitination | Uniprot | |
| K279 | Acetylation | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K424 | Ubiquitination | Uniprot | |
| K476 | Ubiquitination | Uniprot | |
| K495 | Ubiquitination | Uniprot | |
| Y528 | Phosphorylation | Uniprot | |
| K571 | Ubiquitination | Uniprot | |
| K608 | Ubiquitination | Uniprot | |
| S618 | Phosphorylation | Uniprot | |
| K678 | Ubiquitination | Uniprot | |
| T688 | Phosphorylation | Uniprot | |
| T701 | Phosphorylation | Uniprot | |
| K731 | Ubiquitination | Uniprot | |
| S736 | Phosphorylation | Uniprot | |
| S740 | Phosphorylation | Uniprot | |
| K742 | Ubiquitination | Uniprot | |
| K751 | Ubiquitination | Uniprot | |
| K762 | Ubiquitination | Uniprot | |
| K768 | Ubiquitination | Uniprot | |
| K811 | Ubiquitination | Uniprot |
研究背景
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Mitochondrion. Nucleus.
Note: Mainly mitochondrial.
Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
Homodimer (By similarity). Interacts with PTCD1.
Belongs to the RNase Z family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
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