产品: | L2HGDH 抗体 |
货号: | DF12159 |
描述: | Rabbit polyclonal antibody to L2HGDH |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 46-48 kDa; 50kD(Calculated). |
蛋白号: | Q9H9P8 |
RRID: | AB_2844964 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12159, RRID:AB_2844964.
展开/折叠
2 hydroxyglutarate dehydrogenase; Alpha hydroxyglutarate oxidoreductase; Alpha ketoglutarate reductase; C14orf160; Duranin; FLJ12618; L alpha hydroxyglutarate dehydrogenase; L-2-hydroxyglutarate dehydrogenase; L-2-hydroxyglutarate dehydrogenase, mitochondrial; L2HDH_HUMAN; l2hgdh; mitochondrial;
抗原和靶标
Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
- Q9H9P8 L2HDH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVPALRYLVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRGDYLLLKPEKCYLVKGNIYPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIKLASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRGPAGVRAQALDRDGNLVEDFVFDAGVGDIGNRILHVRNAPSPAATSSIAISGMIADEVQQRFEL
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9H9P8 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y102 | Phosphorylation | Uniprot | |
Y103 | Phosphorylation | Uniprot | |
K104 | Acetylation | Uniprot | |
K155 | Acetylation | Uniprot | |
K155 | Ubiquitination | Uniprot | |
R165 | Methylation | Uniprot | |
K173 | Acetylation | Uniprot | |
K173 | Ubiquitination | Uniprot | |
K226 | Ubiquitination | Uniprot | |
S232 | Phosphorylation | Uniprot | |
K243 | Ubiquitination | Uniprot | |
S270 | Phosphorylation | Uniprot | |
Y285 | Phosphorylation | Uniprot | |
K297 | Ubiquitination | Uniprot | |
K334 | Acetylation | Uniprot | |
S440 | Phosphorylation | Uniprot |
研究背景
Mitochondrion.
Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
Belongs to the L2HGDH family.
研究领域
· Metabolism > Carbohydrate metabolism > Butanoate metabolism.
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