产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12187, RRID:AB_2844992.
展开/折叠
Annexin A7; Annexin VII; Annexin-7; ANX7; ANXA7; ANXA7_HUMAN; SNX; Synexin;
抗原和靶标
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
- P20073 ANXA7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVGQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P20073 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K196 | Acetylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K233 | Acetylation | Uniprot | |
| K233 | Ubiquitination | Uniprot | |
| K237 | Ubiquitination | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| T275 | Phosphorylation | Uniprot | |
| T286 | Phosphorylation | Uniprot | |
| C298 | S-Nitrosylation | Uniprot | |
| K309 | Ubiquitination | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| Y402 | Phosphorylation | Uniprot | |
| Y426 | Phosphorylation | Uniprot | |
| Y427 | Phosphorylation | Uniprot | |
| K430 | Acetylation | Uniprot | |
| K430 | Ubiquitination | Uniprot | |
| S447 | Phosphorylation | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| S475 | Phosphorylation | Uniprot | |
| Y478 | Phosphorylation | Uniprot |
研究背景
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
Interacts with PDCD6.
A pair of annexin repeats may form one binding site for calcium and phospholipid.
Belongs to the annexin family.
限制条款
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