(1)
(11)
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12216, RRID:AB_2845021.
展开/折叠
Adenocarcinoma antigen recognized by T lymphocytes 4; ART 4; ART4; MST158; MSTP158; Nin one binding protein; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); nob1; NOB1_HUMAN; NOB1P; Phosphorylation regulatory protein HP-10; Protein ART-4; Protein ART4; PSMD8 binding protein 1; PSMD8BP1; RNA binding protein NOB1; RNA-binding protein NOB1;
抗原和靶标
- Q9ULX3 NOB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPETPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9ULX3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K25 | Ubiquitination | Uniprot | |
| T35 | Phosphorylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| T42 | Phosphorylation | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| Y62 | Phosphorylation | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| K72 | Ubiquitination | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| T121 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K133 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| T140 | Phosphorylation | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| T210 | Phosphorylation | Uniprot | |
| K275 | Methylation | Uniprot | |
| K275 | Ubiquitination | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| K291 | Ubiquitination | Uniprot | |
| T292 | Phosphorylation | Uniprot | |
| K315 | Ubiquitination | Uniprot | |
| Y324 | Phosphorylation | Uniprot | |
| S325 | Phosphorylation | Uniprot | |
| T328 | Phosphorylation | Uniprot | |
| K330 | Ubiquitination | Uniprot | |
| K333 | Acetylation | Uniprot | |
| K333 | Ubiquitination | Uniprot | |
| Y334 | Phosphorylation | Uniprot | |
| T341 | Phosphorylation | Uniprot | |
| R345 | Methylation | Uniprot | |
| S352 | Phosphorylation | Uniprot | |
| K358 | Ubiquitination | Uniprot | |
| T359 | Phosphorylation | Uniprot | |
| Y366 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| R396 | Methylation | Uniprot | |
| S404 | Phosphorylation | Uniprot |
研究背景
May play a role in mRNA degradation (Probable). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity).
Nucleus.
Detected in liver, lung, placenta, endothelial cells and spleen.
Interacts with UPF2 (Probable). Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
Belongs to the NOB1 family.
研究领域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
文献引用
Application: WB Species: Human Sample: FaDu cells
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