产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12273, RRID:AB_2845078.
展开/折叠
EPP; FCE; Fch; Fcl; fech; Ferrochelatase (protoporphyria); Ferrochelatase; Ferrochelatase mitochondrial; Heme synthase; Heme synthetase; HEMH_HUMAN; mitochondrial; Protoheme ferro lyase; Protoheme ferro-lyase; Protoporphyria;
抗原和靶标
- P22830 HEMH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P22830 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K37 | Acetylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| T315 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| K320 | Ubiquitination | Uniprot | |
| K415 | Acetylation | Uniprot | |
| S420 | Phosphorylation | Uniprot |
研究背景
Catalyzes the ferrous insertion into protoporphyrin IX.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Homodimer.
Belongs to the ferrochelatase family.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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