| 产品: | ASBT 抗体 |
| 货号: | DF12351 |
| 描述: | Rabbit polyclonal antibody to ASBT |
| 应用: | WB IHC |
| 反应: | Human, Mouse |
| 分子量: | 38-40 kDa; 38kD(Calculated). |
| 蛋白号: | Q12908 |
| RRID: | AB_2845156 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12351, RRID:AB_2845156.
展开/折叠
Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal; ileal apical sodium-dependent bile acid transporter; Ileal Na(+)/bile acid cotransporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na(+)-dependent ileal bile acid transporter; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; NTCP2_HUMAN; PBAM; SLC10A2; Sodium/taurocholate cotransporting polypeptide; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 (sodium/bile acid cotransporter family), member 2; Solute carrier family 10 member 2;
抗原和靶标
A synthesized peptide derived from human ASBT, corresponding to a region within C-terminal amino acids.
- Q12908 NTCP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
翻译修饰 - Q12908 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N10 | N-Glycosylation | Uniprot | |
| K312 | Methylation | Uniprot | |
| K313 | Methylation | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| A339 | Phosphorylation | Uniprot |
研究背景
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
Membrane>Multi-pass membrane protein.
Monomer and homodimer.
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
限制条款
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