| 产品: | CCBL1/KAT1 抗体 |
| 货号: | DF12361 |
| 描述: | Rabbit polyclonal antibody to CCBL1/KAT1 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 48-50 kDa; 48kD(Calculated). |
| 蛋白号: | Q16773 |
| RRID: | AB_2845166 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12361, RRID:AB_2845166.
展开/折叠
Beta lyase; Beta lysase, kidney; CCBL 1; Cysteine conjugate beta lyase; Cysteine conjugate beta lyase, cytoplasmic; Cysteine conjugate beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase); Cysteine S conjugate beta lyase; Cytoplasmic cysteine conjugate beta lyase; FLJ95217; Glutamine phenylpyruvate aminotransferase; Glutamine transaminase K; GTK; KAT1; KATI; Kyneurenine aminotransferase; Kynurenine aminotransferase I; Kynurenine oxoglutarate transaminase 1; MGC29624; OTTHUMP00000022311; OTTHUMP00000022312;
抗原和靶标
- Q16773 KAT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q16773 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Ubiquitination | Uniprot | |
| Y15 | Phosphorylation | Uniprot | |
| T172 | Phosphorylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| T182 | Phosphorylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| K414 | Ubiquitination | Uniprot |
研究背景
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
Cytoplasm.
Homodimer.
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
研究领域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Amino acid metabolism > Tryptophan metabolism.
· Metabolism > Metabolism of other amino acids > Selenocompound metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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