产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12381, RRID:AB_2845186.
展开/折叠
DCTN6; DCTN6_HUMAN; Dynactin 6; Dynactin subunit 6; Dynactin subunit p27; Novel RGD containing protein; p27; Protein WS-3; Protein WS3; WS 3; WS3;
抗原和靶标
- O00399 DCTN6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTMKGSSTPVKN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O00399 作为底物
研究背景
Phosphorylation at Thr-186 by CDK1 during mitotic prometaphase creates a binding site for PLK1 that facilitates its recruitment to kinetochores.
Cytoplasm>Cytoskeleton. Chromosome>Centromere>Kinetochore.
Ubiquitous.
Member of the pointed-end complex of the dynactin shoulder complex which contains DCTN4, DCTN5 and DCTN6 subunits and ACTR10. Within the complex DCTN6 forms a heterodimer with DCTN5. Interacts with PLK1.
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
研究领域
· Organismal Systems > Excretory system > Vasopressin-regulated water reabsorption.
限制条款
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