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| 产品: | GSTM3 抗体 |
| 货号: | DF12408 |
| 描述: | Rabbit polyclonal antibody to GSTM3 |
| 应用: | WB IHC |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 27-29 kDa; 27kD(Calculated). |
| 蛋白号: | P21266 |
| RRID: | AB_2845213 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12408, RRID:AB_2845213.
展开/折叠
brain GST; brain type mu glutathione S transferase; glutathione S alkyltransferase M3; glutathione S aryltransferase M3; glutathione S transferase M3 (brain); glutathione S transferase M3; Glutathione S transferase Mu 3; glutathione S transferase, Mu 3; Glutathione S-transferase Mu 3; GST class mu 3; GST class-mu 3; GST5; GSTB; Gstm3; GSTM3-3; GSTM3_HUMAN; GTM3; hGSTM3-3; MGC3310; MGC3704; S (hydroxyalkyl)glutathione lyase M3;
抗原和靶标
- P21266 GSTM3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P21266 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| T28 | Phosphorylation | Uniprot | |
| T30 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| C39 | S-Nitrosylation | Uniprot | |
| R47 | Methylation | Uniprot | |
| K54 | Sumoylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| Y66 | Phosphorylation | Uniprot | |
| K71 | Acetylation | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| T75 | Phosphorylation | Uniprot | |
| R82 | Methylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| K128 | Sumoylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| C208 | S-Nitrosylation | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| K222 | Ubiquitination | Uniprot |
研究背景
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.
The N-terminus is blocked.
Cytoplasm.
Testis and brain.
Homodimer.
Belongs to the GST superfamily. Mu family.
研究领域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
文献引用
Application: WB Species: human Sample: U251 cells
限制条款
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