产品: | NSDHL 抗体 |
货号: | DF12432 |
描述: | Rabbit polyclonal antibody to NSDHL |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
分子量: | 42 kDa,40 kDa; 42kD(Calculated). |
蛋白号: | Q15738 |
RRID: | AB_2845237 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12432, RRID:AB_2845237.
展开/折叠
decarboxylating; H105E3; H105e3 protein; NAD(P) dependent steroid dehydrogenase like; NSDHL; NSDHL_HUMAN; Protein H105e3; SDR31E1; Short chain dehydrogenase/reductase family 31E member 1; Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating; Sterol-4-alpha-carboxylate 3-dehydrogenase; XAP104;
抗原和靶标
- Q15738 NSDHL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q15738 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
M1 | Acetylation | Uniprot | |
T19 | Phosphorylation | Uniprot | |
T22 | Phosphorylation | Uniprot | |
K24 | Ubiquitination | Uniprot | |
K31 | Ubiquitination | Uniprot | |
S87 | Phosphorylation | Uniprot | |
K96 | Ubiquitination | Uniprot | |
S106 | Phosphorylation | Uniprot | |
K114 | Ubiquitination | Uniprot | |
K126 | Ubiquitination | Uniprot | |
K133 | Ubiquitination | Uniprot | |
S147 | Phosphorylation | Uniprot | |
Y164 | Phosphorylation | Uniprot | |
K167 | Ubiquitination | Uniprot | |
K176 | Ubiquitination | Uniprot | |
K191 | Ubiquitination | Uniprot | |
K232 | Ubiquitination | Uniprot | |
K263 | Ubiquitination | Uniprot | |
T284 | Phosphorylation | Uniprot | |
Y288 | Phosphorylation | Uniprot | |
K345 | Ubiquitination | Uniprot | |
Y349 | Phosphorylation | Uniprot | |
T354 | Phosphorylation | Uniprot |
研究背景
Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.
Endoplasmic reticulum membrane>Single-pass membrane protein. Lipid droplet.
Note: Trafficking through the Golgi is necessary for ER membrane localization.
Brain, heart, liver, lung, kidney, skin and placenta.
Belongs to the 3-beta-HSD family.
研究领域
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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