产品: | OXA1L 抗体 |
货号: | DF12437 |
描述: | Rabbit polyclonal antibody to OXA1L |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 42 kDa; 49kD(Calculated). |
蛋白号: | Q15070 |
RRID: | AB_2845242 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12437, RRID:AB_2845242.
展开/折叠
HSA; Mitochondrial inner membrane protein OXA1L; OXA1; OXA1 like protein; OXA1-like protein; OXA1Hs; Oxa1l; OXA1L_HUMAN; Oxidase (cytochrome c) assembly 1 like; Oxidase assembly 1 like protein; Oxidase assembly 1-like protein;
抗原和靶标
- Q15070 OXA1L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAMGLMCGRRELLRLLQSGRRVHSVAGPSQWLGKPLTTRLLFPVAPCCCRPHYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAACTVFARCLIFPLIVTGQREAARIHNHLPEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAETGVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAARGPLRQTFTHNPLLQPGKDNPPNIPSSSSKPKSKYPWHDTLG
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q15070 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K178 | Ubiquitination | Uniprot | |
K187 | Ubiquitination | Uniprot | |
K197 | Ubiquitination | Uniprot | |
T340 | Phosphorylation | Uniprot | |
K343 | Ubiquitination | Uniprot | |
K354 | Ubiquitination | Uniprot | |
S364 | Phosphorylation | Uniprot | |
K366 | Ubiquitination | Uniprot | |
K370 | Ubiquitination | Uniprot | |
R394 | Methylation | Uniprot | |
T400 | Phosphorylation | Uniprot | |
T402 | Phosphorylation | Uniprot | |
K411 | Ubiquitination | Uniprot |
研究背景
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.
Mitochondrion inner membrane>Multi-pass membrane protein.
Monomer; predominantly monomeric at low salt concentrations. Homooligomer; predominantly homooligomeric at high salt concentrations. Homodimer. Homotetramer. Interacts with MRPL13, MRPL20, MRPL28, MRPL48, MRPL49 and MRPL51. Associates preferentially as a dimer with the large ribosomal subunit 39S of the mitochondrial ribosome.
Belongs to the OXA1/ALB3/YidC family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > Protein export.
限制条款
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