| 产品: | PDE6A 抗体 |
| 货号: | DF12446 |
| 描述: | Rabbit polyclonal antibody to PDE6A |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 100-110 kDa; 100kD(Calculated). |
| 蛋白号: | P16499 |
| RRID: | AB_2845251 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12446, RRID:AB_2845251.
展开/折叠
5''-cyclic phosphodiesterase subunit alpha; CGPR A; GMP PDE alpha; GMP-PDE alpha; PDE 6 alpha; PDE 6A; PDE V B1; PDE V-B1; PDE6A; PDE6A_HUMAN; PDEA; Phosphodiesterase 6 alpha; Phosphodiesterase 6A alpha subunit; Phosphodiesterase 6A cGMP specific rod alpha; Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha; Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit; Rod cGMP-specific 3'';
抗原和靶标
- P16499 PDE6A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGEVTAEEVEKFLDSNIGFAKQYYNLHYRAKLISDLLGAKEAAVDFSNYHSPSSMEESEIIFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMPDQEIVFPLDMGIVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILASPIMNGKDVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVPPYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPAYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYDAKMKVQEEKKQKQQSAKSAAAGNQPGGNPSPGGATTSKSCCIQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P16499 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K84 | Methylation | Uniprot | |
| S180 | Phosphorylation | Uniprot | |
| Y264 | Phosphorylation | Uniprot | |
| Y275 | Phosphorylation | Uniprot | |
| T283 | Phosphorylation | Uniprot | |
| K467 | Acetylation | Uniprot | |
| K677 | Acetylation | Uniprot | |
| T717 | Phosphorylation | Uniprot |
研究背景
This protein participates in processes of transmission and amplification of the visual signal.
Cell membrane>Lipid-anchor>Cytoplasmic side.
Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.
Belongs to the cyclic nucleotide phosphodiesterase family.
研究领域
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Organismal Systems > Sensory system > Phototransduction.
限制条款
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