产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0242, RRID:AB_2833417.
展开/折叠
NEF 4; NEF4; Neurofilament 4 (57kD); Neurofilament 4; Perf; PERI_HUMAN; Peripherin; PRPH 1; prph; PRPH1;
抗原和靶标
- P41219 PERI_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSHHPSGLRAGFSSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSASPSSSVRLGSFRSPRAGAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQKEQRSELDKSSAHSY
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P41219 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S13 | Phosphorylation | Uniprot | |
Y17 | Phosphorylation | Uniprot | |
S28 | Phosphorylation | Uniprot | |
S50 | Phosphorylation | Uniprot | |
S59 | Phosphorylation | P31749 (AKT1) | Uniprot |
S62 | Phosphorylation | Uniprot | |
S75 | Phosphorylation | Uniprot | |
K98 | Methylation | Uniprot | |
Y287 | Phosphorylation | Uniprot | |
K288 | Acetylation | Uniprot | |
K288 | Ubiquitination | Uniprot | |
K290 | Ubiquitination | Uniprot | |
K398 | Acetylation | Uniprot | |
K398 | Sumoylation | Uniprot | |
K398 | Ubiquitination | Uniprot | |
S405 | Phosphorylation | Uniprot | |
S413 | Phosphorylation | Uniprot | |
T421 | Phosphorylation | Uniprot | |
Y470 | Phosphorylation | Uniprot |
研究背景
Class-III neuronal intermediate filament protein.
Belongs to the intermediate filament family.
研究领域
· Human Diseases > Neurodegenerative diseases > Amyotrophic lateral sclerosis (ALS).
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