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| 产品: | PERM 抗体 |
| 货号: | DF12528 |
| 描述: | Rabbit polyclonal antibody to PERM |
| 应用: | WB |
| 反应: | Human |
| 预测: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 84 kDa; 84kD(Calculated). |
| 蛋白号: | P05164 |
| RRID: | AB_2845490 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12528, RRID:AB_2845490.
展开/折叠
84 kDa myeloperoxidase; 89 kDa myeloperoxidase; EC 1.11.1.7; EC1.11.2.2; fj80f04; MPO; mpx; myeloid-specific peroxidase; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain; PERM_HUMAN; wu:fj80f04;
抗原和靶标
- P05164 PERM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREAS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P05164 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K103 | Acetylation | Uniprot | |
| N139 | N-Glycosylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| N323 | N-Glycosylation | Uniprot | |
| N355 | N-Glycosylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| N391 | N-Glycosylation | Uniprot | |
| T428 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| Y500 | Phosphorylation | Uniprot | |
| Y516 | Phosphorylation | Uniprot | |
| S528 | Phosphorylation | Uniprot | |
| K625 | Sumoylation | Uniprot | |
| S720 | Phosphorylation | Uniprot | |
| Y723 | Phosphorylation | Uniprot | |
| N729 | N-Glycosylation | Uniprot |
研究背景
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Lysosome.
Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain.
Belongs to the peroxidase family. XPO subfamily.
研究领域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
· Human Diseases > Cancers: Specific types > Acute myeloid leukemia. (View pathway)
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
文献引用
Application: WB Species: Rat Sample: Liver
限制条款
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