| 产品: | ADI1 抗体 |
| 货号: | DF12555 |
| 描述: | Rabbit polyclonal antibody to ADI1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 分子量: | 20 kDa; 21kD(Calculated). |
| 蛋白号: | Q9BV57 |
| RRID: | AB_2845517 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12555, RRID:AB_2845517.
展开/折叠
1 2 dihydroxy 3 keto 5 methylthiopentene dioxygenase; 1; 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Aci reductone dioxygenase; Acireductone dioxygenase (Fe(2+) requiring); Acireductone dioxygenase (Ni(2+) requiring); Acireductone dioxygenase (Ni(2+)-requiring); Acireductone dioxygenase 1; ADI 1; Adi1; ADI1 antibody; APL1; ARD; EC 1.13.; Fe ARD; FLJ10913; HMFT1638; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MT1 MMP cytoplasmic tail binding protein 1; MTCBP 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD; SIPL; Submergence induced protein 2; Submergence induced protein 2 homolog; Submergence induced protein like factor; Submergence-induced protein 2 homolog;
抗原和靶标
Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.
- Q9BV57 MTND_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVQAWYMDDAPGDPRQPHRPDPGRPVGLEQLRRLGVLYWKLDADKYENDPELEKIRRERNYSWMDIITICKDKLPNYEEKIKMFYEEHLHLDDEIRYILDGSGYFDVRDKEDQWIRIFMEKGDMVTLPAGIYHRFTVDEKNYTKAMRLFVGEPVWTAYNRPADHFEARGQYVKFLAQTA
翻译修饰 - Q9BV57 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R32 | Methylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| Y46 | Phosphorylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K73 | Acetylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| S102 | Phosphorylation | Uniprot | |
| Y104 | Phosphorylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| K173 | Ubiquitination | Uniprot |
研究背景
Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
Cytoplasm. Nucleus. Cell membrane>Peripheral membrane protein>Cytoplasmic side.
Note: Localizes to the plasma membrane when complexed to MMP14.
Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.
Monomer (By similarity). Interacts with MMP14.
Belongs to the acireductone dioxygenase (ARD) family.
研究领域
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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