| 产品: | ATP6V1E1 抗体 |
| 货号: | DF12565 |
| 描述: | Rabbit polyclonal antibody to ATP6V1E1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 31 kDa; 26kD(Calculated). |
| 蛋白号: | P36543 |
| RRID: | AB_2845527 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12565, RRID:AB_2845527.
抗原和靶标
- P36543 VATE1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P36543 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| K10 | Ubiquitination | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| K52 | Acetylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| Y57 | Phosphorylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| K191 | Acetylation | Uniprot | |
| K191 | Ubiquitination | Uniprot |
研究背景
Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Ubiquitous. High expression in the skin.
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d). Interacts with RABL2/RABL2A; binds preferentially to GTP-bound RABL2 (By similarity). Interacts with ALDOC. Interacts with RAB11B.
Belongs to the V-ATPase E subunit family.
研究领域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Environmental Information Processing > Signal transduction > mTOR signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.
· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.
· Human Diseases > Immune diseases > Rheumatoid arthritis.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Synaptic vesicle cycle.
· Organismal Systems > Excretory system > Collecting duct acid secretion.
限制条款
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