产品: | CPOX 抗体 |
货号: | DF12588 |
描述: | Rabbit polyclonal antibody to CPOX |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Rabbit |
分子量: | 36 kDa; 50kD(Calculated). |
蛋白号: | P36551 |
RRID: | AB_2845550 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12588, RRID:AB_2845550.
展开/折叠
Coprogen oxidase; COPROPORPHYRIA; Coproporphyrinogen III oxidase; Coproporphyrinogen Oxidase (CPOX); Coproporphyrinogen-III oxidase; Coproporphyrinogenase; COX; CPO; Cpox; CPX; HEM 6; Hem-6; Hem6; HEM6_HUMAN; mitochondrial;
抗原和靶标
- P36551 HEM6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P36551 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S112 | Phosphorylation | Uniprot | |
K184 | Ubiquitination | Uniprot | |
K220 | Ubiquitination | Uniprot | |
R298 | Methylation | Uniprot | |
K301 | Ubiquitination | Uniprot | |
K314 | Ubiquitination | Uniprot | |
K347 | Ubiquitination | Uniprot | |
S356 | Phosphorylation | Uniprot | |
K370 | Ubiquitination | Uniprot | |
K404 | Acetylation | Uniprot | |
K404 | Ubiquitination | Uniprot | |
T409 | Phosphorylation | Uniprot | |
S416 | Phosphorylation | Uniprot | |
S420 | Phosphorylation | Uniprot | |
T424 | Phosphorylation | Uniprot | |
K438 | Ubiquitination | Uniprot |
研究背景
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
Mitochondrion intermembrane space.
Homodimer.
Belongs to the aerobic coproporphyrinogen-III oxidase family.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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