产品: | CTPS2 抗体 |
货号: | DF12590 |
描述: | Rabbit polyclonal antibody to CTPS2 |
应用: | WB IF/ICC |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 66 kDa; 66kD(Calculated). |
蛋白号: | Q9NRF8 |
RRID: | AB_2845552 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12590, RRID:AB_2845552.
展开/折叠
CTP synthase 2; CTP synthase II; CTP synthetase 2; CTPS2; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2; FLJ43358; MGC32997; PYRG2_HUMAN; UTP--ammonia ligase 2;
抗原和靶标
- Q9NRF8 PYRG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRYSDASDDSFSEPRIAELEIS
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NRF8 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S12 | Phosphorylation | Uniprot | |
Y53 | Phosphorylation | Uniprot | |
K92 | Ubiquitination | Uniprot | |
K100 | Ubiquitination | Uniprot | |
K169 | Methylation | Uniprot | |
T189 | Phosphorylation | Uniprot | |
K195 | Ubiquitination | Uniprot | |
R205 | Methylation | Uniprot | |
S261 | Phosphorylation | Uniprot | |
K264 | Ubiquitination | Uniprot | |
S277 | Phosphorylation | Uniprot | |
Y336 | Phosphorylation | Uniprot | |
K353 | Ubiquitination | Uniprot | |
K360 | Ubiquitination | Uniprot | |
T378 | Phosphorylation | Uniprot | |
R389 | Methylation | Uniprot | |
K466 | Ubiquitination | Uniprot | |
S562 | Phosphorylation | Uniprot | |
S563 | Phosphorylation | Uniprot | |
S564 | Phosphorylation | Uniprot | |
R566 | Methylation | Uniprot | |
Y567 | Phosphorylation | Uniprot | |
S568 | Phosphorylation | P48729 (CSNK1A1) | Uniprot |
S571 | Phosphorylation | Uniprot | |
S574 | Phosphorylation | Uniprot | |
S576 | Phosphorylation | Uniprot |
研究背景
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
Belongs to the CTP synthase family.
研究领域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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