| 产品: | GART 抗体 |
| 货号: | DF12613 |
| 描述: | Rabbit polyclonal antibody to GART |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus |
| 分子量: | 108 kDa; 108kD(Calculated). |
| 蛋白号: | P22102 |
| RRID: | AB_2845575 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12613, RRID:AB_2845575.
展开/折叠
5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; GAR transformylase; GARS; GART; GARTF; Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylglycinamide formyltransferase; Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide synthetase; PRGS; PUR2_HUMAN; Trifunctional purine biosynthetic protein adenosine 3;
抗原和靶标
- P22102 PUR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P22102 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| R13 | Methylation | Uniprot | |
| K20 | Methylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K28 | Acetylation | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| C41 | S-Nitrosylation | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| K44 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K65 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| C93 | S-Nitrosylation | Uniprot | |
| K107 | Acetylation | Uniprot | |
| K107 | Ubiquitination | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| R116 | Methylation | Uniprot | |
| T121 | Phosphorylation | Uniprot | |
| K125 | Methylation | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| K129 | Ubiquitination | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| K219 | Acetylation | Uniprot | |
| K219 | Ubiquitination | Uniprot | |
| T230 | Phosphorylation | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K251 | Ubiquitination | Uniprot | |
| K281 | Ubiquitination | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| C298 | S-Nitrosylation | Uniprot | |
| Y348 | Phosphorylation | Uniprot | |
| T349 | Phosphorylation | Uniprot | |
| K350 | Acetylation | Uniprot | |
| K350 | Ubiquitination | Uniprot | |
| K375 | Ubiquitination | Uniprot | |
| K378 | Ubiquitination | Uniprot | |
| S398 | Phosphorylation | Uniprot | |
| K404 | Ubiquitination | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| K411 | Ubiquitination | Uniprot | |
| Y417 | Phosphorylation | Uniprot | |
| K419 | Ubiquitination | Uniprot | |
| R433 | Methylation | Uniprot | |
| K438 | Ubiquitination | Uniprot | |
| S440 | Phosphorylation | Uniprot | |
| K452 | Ubiquitination | Uniprot | |
| K453 | Ubiquitination | Uniprot | |
| K459 | Ubiquitination | Uniprot | |
| S464 | Phosphorylation | Uniprot | |
| K467 | Ubiquitination | Uniprot | |
| K480 | Methylation | Uniprot | |
| K480 | Ubiquitination | Uniprot | |
| K485 | Ubiquitination | Uniprot | |
| T498 | Phosphorylation | Uniprot | |
| K499 | Ubiquitination | Uniprot | |
| K501 | Ubiquitination | Uniprot | |
| K557 | Ubiquitination | Uniprot | |
| K561 | Ubiquitination | Uniprot | |
| K598 | Ubiquitination | Uniprot | |
| S625 | Phosphorylation | Uniprot | |
| K633 | Ubiquitination | Uniprot | |
| S672 | Phosphorylation | Uniprot | |
| K676 | Ubiquitination | Uniprot | |
| T682 | Phosphorylation | Uniprot | |
| K697 | Ubiquitination | Uniprot | |
| S714 | Phosphorylation | Uniprot | |
| S723 | Phosphorylation | Uniprot | |
| K743 | Ubiquitination | Uniprot | |
| K757 | Ubiquitination | Uniprot | |
| K779 | Ubiquitination | Uniprot | |
| S784 | Phosphorylation | Uniprot | |
| S796 | Phosphorylation | Uniprot | |
| T798 | Phosphorylation | Uniprot | |
| S802 | Phosphorylation | Uniprot | |
| K844 | Acetylation | Uniprot | |
| K852 | Acetylation | Uniprot | |
| K852 | Ubiquitination | Uniprot | |
| R855 | Methylation | Uniprot | |
| T860 | Phosphorylation | Uniprot | |
| K866 | Ubiquitination | Uniprot | |
| K910 | Ubiquitination | Uniprot | |
| K977 | Ubiquitination | Uniprot | |
| K982 | Acetylation | Uniprot |
研究背景
In the N-terminal section; belongs to the GARS family.
In the central section; belongs to the AIR synthase family.
In the C-terminal section; belongs to the GART family.
研究领域
· Human Diseases > Drug resistance: Antineoplastic > Antifolate resistance.
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Metabolism of cofactors and vitamins > One carbon pool by folate.
· Metabolism > Global and overview maps > Metabolic pathways.
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