| 产品: | GGPS1 抗体 |
| 货号: | DF12617 |
| 描述: | Rabbit polyclonal antibody to GGPS1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 35 kDa; 35kD(Calculated). |
| 蛋白号: | O95749 |
| RRID: | AB_2845579 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12617, RRID:AB_2845579.
展开/折叠
(2E; 6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase 1; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; Geranylgeranyl pyrophosphate synthetase; Geranyltranstransferase; GGPP synthase; GGPP synthetase; GGPPS; GGPPS_HUMAN; GGPPS1; GGPPSase; GGPS1; OTTHUMP00000036073; OTTHUMP00000216161; OTTHUMP00000216163; OTTHUMP00000216164;
抗原和靶标
- O95749 GGPPS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O95749 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K3 | Ubiquitination | Uniprot | |
| Y16 | Phosphorylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K25 | Acetylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| S87 | Phosphorylation | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| S203 | Phosphorylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| Y272 | Phosphorylation | Uniprot | |
| K273 | Ubiquitination | Uniprot | |
| R278 | Methylation | Uniprot |
研究背景
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
Cytoplasm.
Abundantly expressed in testis. Found in other tissues to a lower extent.
Homohexamer; trimer of homodimers.
Belongs to the FPP/GGPP synthase family.
研究领域
· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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