产品: | GSTA2 抗体 |
货号: | DF12623 |
描述: | Rabbit polyclonal antibody to GSTA2 |
应用: | WB |
反应: | Human, Mouse, Rat |
分子量: | 26 kDa; 26kD(Calculated). |
蛋白号: | P09210 |
RRID: | AB_2845585 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12623, RRID:AB_2845585.
展开/折叠
EC 2.5.1.18; Glutathione S transferase 2; Glutathione S transferase A2; Glutathione S-alkyltransferase A2; Glutathione S-aralkyltransferase A2; Glutathione S-aryltransferase A2; Glutathione S-transferase alpha 2; Glutathione S-transferase GT41A; Glutathione S-transferase Ya-2; Glutathione S-transferase, alpha 2 (Yc2); GST 1b-1b; GST A2-2; GST class alpha member 2; GST gamma; GST HA subunit 2; GST Ya2; GST, class alpha, 2; GST2; Gst2-2; GSTA2 2; GSTA2-2; Gstc-2; Gstc2; GTA2; GTH2; HA subunit 2; Liver GST2; MGC10525; OTTHUMP00000017883; S-(hydroxyalkyl)glutathione lyase A2;
抗原和靶标
- P09210 GSTA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
翻译修饰 - P09210 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y9 | Phosphorylation | Uniprot | |
S10 | Phosphorylation | Uniprot | |
S37 | Phosphorylation | Uniprot | |
Y49 | Phosphorylation | Uniprot | |
Y74 | Phosphorylation | Uniprot | |
S77 | Phosphorylation | Uniprot | |
Y79 | Phosphorylation | Uniprot | |
Y82 | Phosphorylation | Uniprot | |
K84 | Acetylation | Uniprot | |
Y132 | Phosphorylation | Uniprot | |
S142 | Phosphorylation | Uniprot | |
Y147 | Phosphorylation | Uniprot | |
K152 | Acetylation | Uniprot | |
S154 | Phosphorylation | Uniprot | |
S176 | Phosphorylation | Uniprot | |
S177 | Phosphorylation | Uniprot | |
S189 | Phosphorylation | Uniprot | |
T193 | Phosphorylation | Uniprot | |
K195 | Acetylation | Uniprot | |
K196 | Acetylation | Uniprot | |
S202 | Phosphorylation | Uniprot | |
S212 | Phosphorylation | Uniprot |
研究背景
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Cytoplasm.
Liver.
Homodimer or heterodimer of GSTA1 and GSTA2.
Belongs to the GST superfamily. Alpha family.
研究领域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
文献引用
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