| 产品: | ISYNA1 抗体 |
| 货号: | DF12646 |
| 描述: | Rabbit polyclonal antibody to ISYNA1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Bovine, Horse, Sheep, Dog |
| 分子量: | 61 kDa; 61kD(Calculated). |
| 蛋白号: | Q9NPH2 |
| RRID: | AB_2845608 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12646, RRID:AB_2845608.
展开/折叠
hINO1; hIPS; INO1; INO1_HUMAN; INOS; Inositol 3 phosphate synthase 1; Inositol-3-phosphate synthase 1; IPS; IPS 1; ISYNA 1; Isyna1; MI 1 P synthase; MI-1-P synthase; MI1P synthase; MIP synthase; Myo inositol 1 phosphate synthase A1; Myo-inositol 1-phosphate synthase A1; Myo-inositol-1-phosphate synthase;
抗原和靶标
Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
- Q9NPH2 INO1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVFVPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYIPEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPGLNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMPTT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NPH2 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K40 | Ubiquitination | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| R208 | Methylation | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K312 | Ubiquitination | Uniprot | |
| K356 | Ubiquitination | Uniprot | |
| S392 | Phosphorylation | Uniprot | |
| K393 | Ubiquitination | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| S484 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| K516 | Methylation | Uniprot | |
| K516 | Ubiquitination | Uniprot | |
| T524 | Phosphorylation | Uniprot | |
| Y525 | Phosphorylation | Uniprot | |
| K530 | Ubiquitination | Uniprot | |
| T538 | Phosphorylation | Uniprot | |
| T557 | Phosphorylation | Uniprot | |
| T558 | Phosphorylation | Uniprot |
研究背景
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
Cytoplasm.
Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
Belongs to the myo-inositol 1-phosphate synthase family.
研究领域
· Metabolism > Carbohydrate metabolism > Inositol phosphate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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