产品: | LAP3 抗体 |
货号: | DF12651 |
描述: | Rabbit polyclonal antibody to LAP3 |
应用: | WB |
反应: | Human, Mouse, Rat |
预测: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 56 kDa; 56kD(Calculated). |
蛋白号: | P28838 |
RRID: | AB_2845613 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12651, RRID:AB_2845613.
展开/折叠
AMPL_HUMAN; Cytosol aminopeptidase; epididymis secretory protein Li 106; HEL-S-106; LAP 3; LAP; LAP-3; Lap3; LAPEP; Leucine aminopeptidase 3; Leucyl aminopeptidase; PEPS; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase;
抗原和靶标
- P28838 AMPL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFDKLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQVDNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P28838 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S26 | Phosphorylation | Uniprot | |
S28 | Phosphorylation | Uniprot | |
T29 | Phosphorylation | Uniprot | |
S42 | Phosphorylation | Uniprot | |
K45 | Ubiquitination | Uniprot | |
S54 | Phosphorylation | Uniprot | |
K61 | Acetylation | Uniprot | |
K61 | Ubiquitination | Uniprot | |
K103 | Acetylation | Uniprot | |
K104 | Acetylation | Uniprot | |
K118 | Ubiquitination | Uniprot | |
S138 | Phosphorylation | Uniprot | |
S139 | Phosphorylation | Uniprot | |
S180 | Phosphorylation | Uniprot | |
K188 | Ubiquitination | Uniprot | |
S194 | Phosphorylation | Uniprot | |
T211 | Phosphorylation | Uniprot | |
K221 | Acetylation | Uniprot | |
K221 | Ubiquitination | Uniprot | |
K229 | Ubiquitination | Uniprot | |
S238 | Phosphorylation | Uniprot | |
S288 | Phosphorylation | Uniprot | |
S296 | Phosphorylation | Uniprot | |
T311 | Phosphorylation | Uniprot | |
K356 | Ubiquitination | Uniprot | |
T363 | Phosphorylation | Uniprot | |
C445 | S-Nitrosylation | Uniprot | |
K455 | Acetylation | Uniprot | |
K455 | Ubiquitination | Uniprot | |
Y456 | Phosphorylation | Uniprot | |
S458 | Phosphorylation | Uniprot | |
K469 | Ubiquitination | Uniprot | |
K476 | Ubiquitination | Uniprot | |
K489 | Acetylation | Uniprot |
研究背景
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Cytoplasm.
Homohexamer.
Belongs to the peptidase M17 family.
研究领域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
文献引用
Application: WB Species: Human Sample: BMECs
Application: IHC Species: Human Sample: breast cancer cell
限制条款
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