| 产品: | P5CS 抗体 |
| 货号: | DF12683 |
| 描述: | Rabbit polyclonal antibody to P5CS |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 87 kDa; 87kD(Calculated). |
| 蛋白号: | P54886 |
| RRID: | AB_2845645 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12683, RRID:AB_2845645.
展开/折叠
2810433K04Rik; AI429789; Aldehyde dehydrogenase 18 family member A1; Aldehyde dehydrogenase 18A1; Aldehyde dehydrogenase family 18 member A1; ALDH18A1; Delta 1 pyrroline 5 carboxylate synthetase; Delta1 pyrroline 5 carboxlate synthetase; Gamma-glutamyl kinase; Gamma-glutamyl phosphate reductase; GK; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; GPR; GSAS; MGC117316; MGC32233; P5CS; P5CS_HUMAN; PYCS; Pyrroline 5 carboxylate synthetase (glutamate gamma semialdehyde synthetase);
抗原和靶标
- P54886 P5CS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLSQVYRCGFQPFNQHLLPWVKCTTVFRSHCIQPSVIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNQLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLANKKDLEEAEGRLAAPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDNVQDAIDHIHKYGSSHTDVIVTEDENTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGKDHVVSDFSEHGSLKYLHENLPIPQRNTN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P54886 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S79 | Phosphorylation | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| K124 | Methylation | Uniprot | |
| S136 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| K149 | Acetylation | Uniprot | |
| R212 | Methylation | Uniprot | |
| K300 | Ubiquitination | Uniprot | |
| K347 | Acetylation | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| K348 | Ubiquitination | Uniprot | |
| K408 | Ubiquitination | Uniprot | |
| K409 | Acetylation | Uniprot | |
| K424 | Ubiquitination | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| K432 | Ubiquitination | Uniprot | |
| S450 | Phosphorylation | Uniprot | |
| T538 | Phosphorylation | Uniprot | |
| K550 | Ubiquitination | Uniprot | |
| K605 | Ubiquitination | Uniprot | |
| C606 | S-Nitrosylation | Uniprot | |
| C612 | S-Nitrosylation | Uniprot | |
| K643 | Ubiquitination | Uniprot | |
| K649 | Acetylation | Uniprot | |
| S657 | Phosphorylation | Uniprot | |
| S659 | Phosphorylation | Uniprot | |
| K662 | Ubiquitination | Uniprot | |
| T725 | Phosphorylation | Uniprot | |
| R749 | Methylation | Uniprot | |
| T759 | Phosphorylation | Uniprot | |
| K761 | Ubiquitination | Uniprot | |
| K767 | Acetylation | Uniprot | |
| K767 | Ubiquitination | Uniprot | |
| S772 | Phosphorylation | Uniprot | |
| K781 | Ubiquitination | Uniprot |
研究背景
Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine.
Mitochondrion inner membrane.
Homohexamer or homotetramer.
In the N-terminal section; belongs to the glutamate 5-kinase family.
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
研究领域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
限制条款
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