UCK2 Antibody - #DF12789

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产品: UCK2 抗体
货号: DF12789
描述: Rabbit polyclonal antibody to UCK2
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 35 kDa, 40 kDa; 29kD(Calculated).
蛋白号: Q9BZX2
RRID: AB_2845750

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(82%), Rabbit(100%), Dog(82%), Chicken(80%)
克隆:
Polyclonal
特异性:
UCK2 Antibody detects endogenous levels of total UCK2.
RRID:
AB_2845750
引用格式: Affinity Biosciences Cat# DF12789, RRID:AB_2845750.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Cytidine monophosphokinase 2; TSA903; UCK2; UK; UMPK; Uridine cytidine kinase 2; Uridine monophosphokinase 2;

抗原和靶标

免疫原:
Uniprot:

Q9BZX2(UCK2_HUMAN) >>Visit HPA database.

基因/基因ID:
UCK2(7371)
表达:
Q9BZX2 UCK2_HUMAN:

According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific.

序列:
MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKRQTNGCLNGYTPSRKRQASESSSRPH

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Rabbit
100
Sheep
82
Dog
82
Chicken
80
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9BZX2 作为底物

Site PTM Type Enzyme
A2 Acetylation
K33 Ubiquitination
K39 Ubiquitination
Y51 Phosphorylation
K54 Ubiquitination
K73 Ubiquitination
K75 Ubiquitination
K78 Ubiquitination
K96 Ubiquitination
K99 Ubiquitination
K105 Ubiquitination
T157 Phosphorylation
R162 Methylation
T200 Phosphorylation
K201 Ubiquitination
K202 Ubiquitination
K235 Ubiquitination
T238 Phosphorylation
Y245 Phosphorylation
T246 Phosphorylation
S248 Phosphorylation
S254 Phosphorylation

研究背景

功能:

Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

组织特异性:

According to; testis-specific. According to placenta-specific.

亚基结构:

Homotetramer.

蛋白家族:

Belongs to the uridine kinase family.

研究领域

· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.

· Metabolism > Global and overview maps > Metabolic pathways.

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