| 产品: | UCK2 抗体 |
| 货号: | DF12789 |
| 描述: | Rabbit polyclonal antibody to UCK2 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 35 kDa, 40 kDa; 29kD(Calculated). |
| 蛋白号: | Q9BZX2 |
| RRID: | AB_2845750 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12789, RRID:AB_2845750.
展开/折叠
Cytidine monophosphokinase 2; TSA903; UCK2; UK; UMPK; Uridine cytidine kinase 2; Uridine monophosphokinase 2;
抗原和靶标
According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific.
- Q9BZX2 UCK2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKRQTNGCLNGYTPSRKRQASESSSRPH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9BZX2 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K33 | Ubiquitination | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| Y51 | Phosphorylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| K75 | Ubiquitination | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| T157 | Phosphorylation | Uniprot | |
| R162 | Methylation | Uniprot | |
| T200 | Phosphorylation | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| T238 | Phosphorylation | Uniprot | |
| Y245 | Phosphorylation | Uniprot | |
| T246 | Phosphorylation | Uniprot | |
| S248 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot |
研究背景
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
According to; testis-specific. According to placenta-specific.
Homotetramer.
Belongs to the uridine kinase family.
研究领域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
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