| 产品: | UMPS 抗体 |
| 货号: | DF12790 |
| 描述: | Rabbit polyclonal antibody to UMPS |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Rabbit, Dog, Chicken |
| 分子量: | 52 kDa; 52kD(Calculated). |
| 蛋白号: | P11172 |
| RRID: | AB_2845751 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12790, RRID:AB_2845751.
展开/折叠
ODC; OMPdecase; OPRT; OPRTase; Orotate phosphoribosyl transferase and orotidine 5' decarboxylase; Orotate phosphoribosyltransferase; Orotate phosphoribosyltransferase phosphoribosyltransferase; Orotidine 5' phosphate decarboxylase; Orotidine 5''-phosphate decarboxylase; RP11-71H17.9; UMP synthase; Umps; UMPS_HUMAN; Uridine 5' monophosphate synthase; Uridine monophosphate synthetase;
抗原和靶标
- P11172 UMPS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P11172 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| Y16 | Phosphorylation | Uniprot | |
| K22 | Ubiquitination | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| Y37 | Phosphorylation | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K162 | Acetylation | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| C174 | S-Nitrosylation | Uniprot | |
| T175 | Phosphorylation | Uniprot | |
| K178 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| K219 | Ubiquitination | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| S241 | Phosphorylation | Uniprot | |
| K242 | Ubiquitination | Uniprot | |
| K303 | Ubiquitination | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| K323 | Ubiquitination | Uniprot | |
| K324 | Ubiquitination | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| S394 | Phosphorylation | Uniprot | |
| K409 | Ubiquitination | Uniprot | |
| Y432 | Phosphorylation | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| S455 | Phosphorylation | Uniprot | |
| R459 | Methylation | Uniprot | |
| Y466 | Phosphorylation | Uniprot | |
| K468 | Ubiquitination | Uniprot |
研究背景
Homodimer.
In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
In the C-terminal section; belongs to the OMP decarboxylase family.
研究领域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
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