| 产品: | XAB2 抗体 |
| 货号: | DF12798 |
| 描述: | Rabbit polyclonal antibody to XAB2 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Monkey |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 100 kDa; 100kD(Calculated). |
| 蛋白号: | Q9HCS7 |
| RRID: | AB_2845759 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12798, RRID:AB_2845759.
展开/折叠
0610041O14Rik; adapter protein ATH 55; Adapter protein ATH-55; Ath55; AV025587; Crn related protein kim1; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; RNA splicing factor; SYF1; SYF1 homolog; SYF1 homolog, RNA splicing factor; SYF1 pre mRNA splicing factor; SYF1_HUMAN; Xab2; XPA binding protein 2; XPA-binding protein 2;
抗原和靶标
- Q9HCS7 SYF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVVMARLSRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEIQLGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9HCS7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S8 | Phosphorylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| C66 | S-Nitrosylation | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| Y183 | Phosphorylation | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| Y279 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| K389 | Ubiquitination | Uniprot | |
| K393 | Ubiquitination | Uniprot | |
| K420 | Acetylation | Uniprot | |
| K420 | Ubiquitination | Uniprot | |
| K423 | Ubiquitination | Uniprot | |
| K458 | Ubiquitination | Uniprot | |
| Y469 | Phosphorylation | Uniprot | |
| R479 | Methylation | Uniprot | |
| K482 | Ubiquitination | Uniprot | |
| S496 | Phosphorylation | Uniprot | |
| T499 | Phosphorylation | Uniprot | |
| K539 | Ubiquitination | Uniprot | |
| K590 | Ubiquitination | Uniprot | |
| T620 | Phosphorylation | Uniprot | |
| K637 | Ubiquitination | Uniprot | |
| K654 | Ubiquitination | Uniprot | |
| K677 | Ubiquitination | Uniprot | |
| T706 | Phosphorylation | Uniprot | |
| K708 | Ubiquitination | Uniprot | |
| K721 | Ubiquitination | Uniprot | |
| Y734 | Phosphorylation | Uniprot | |
| K770 | Ubiquitination | Uniprot | |
| K794 | Ubiquitination | Uniprot | |
| S851 | Phosphorylation | Uniprot | |
| K853 | Ubiquitination | Uniprot |
研究背景
Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
Nucleus.
Note: Detected in the splicing complex carrying pre-mRNA.
Associates with RNA polymerase II, the TCR-specific proteins CKN1/CSA and ERCC6/CSB, and XPA. Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE. Identified in a pentameric intron-binding (IB) complex composed of AQR, XAB2, ISY1, ZNF830 and PPIE that is incorporated into the spliceosome as a preassembled complex. The IB complex does not contain PRPF19.
Belongs to the crooked-neck family.
研究领域
· Genetic Information Processing > Transcription > Spliceosome.
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