| 产品: | ZNF238 抗体 |
| 货号: | DF12803 |
| 描述: | Rabbit polyclonal antibody to ZNF238 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 59 kDa; 58kD(Calculated). |
| 蛋白号: | Q99592 |
| RRID: | AB_2845764 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12803, RRID:AB_2845764.
展开/折叠
;C2H2171; 58 kDa repressor protein; C2H2 171; RP58; TAZ 1; TAZ-1; TAZ1; Transcriptional repressor RP58; Translin associated zinc finger protein 1; Translin-associated zinc finger protein 1; ZBTB18; Zinc finger and BTB domain containing protein 18; Zinc finger and BTB domain-containing protein 18; Zinc finger protein 238; Zinc finger protein C2H2 171; Zinc finger protein C2H2-171; ZN238_HUMAN; ZNF238;
抗原和靶标
Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
- Q99592 ZBT18_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q99592 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S136 | Phosphorylation | Uniprot | |
| S157 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S279 | Phosphorylation | Uniprot | |
| S283 | Phosphorylation | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| T507 | Phosphorylation | Uniprot | |
| S516 | Phosphorylation | Uniprot | |
| S517 | Phosphorylation | Uniprot |
研究背景
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Nucleus.
Note: Associates with condensed chromatin.
Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
Interacts with DNMT3A.
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
限制条款
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