产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12807, RRID:AB_2845768.
展开/折叠
ACACT2; ACAT 2; ACAT2; Acyl Co A: cholesterol acyltransferase 2; Acyl CoA:cholesterol acyltransferase 2; acyl coenzyme A cholestrol acyltransferase 2; Acyl coenzyme A:cholesterol acyltransferase 2; ARGP2; Cholesterol acyltransferase 2; Sterol O acyl transferase 2; SOAT2;SOAT 2;Sterol O-acyltransferase 2;Cholesterol acyltransferase 2;
抗原和靶标
- O75908 SOAT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O75908 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T285 | Phosphorylation | Uniprot |
研究背景
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Expression seems confined in hepatocytes and enterocytes.
May form homo- or heterodimers.
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
研究领域
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Organismal Systems > Digestive system > Cholesterol metabolism.
限制条款
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